Aydin G Burça, Ciftçi Arbay O, Yalçin Bilgehan, Akçören Zuhal, Cağlar Melda, Senocak Mehmet E, Büyükpamukçu Münevver
Department of Pediatric Oncology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Pediatr Blood Cancer. 2006 Jul;47(1):97-9. doi: 10.1002/pbc.20494.
Metastatic sites other than the lungs, lymph nodes, and liver are unusual for Wilms tumor (WT). Intra-scrotal metastasis is very rare. We report a 3-year-old boy with stage IIA WT, who experienced paratesticular metastasis 2 months after surgery for an abdominal recurrence. He had right scrotal hydrocele at initial diagnosis. The patient underwent right radical orchiectomy, and pathological examination revealed paratesticular WT metastasis. Intra-abdominal and peritoneal disseminated metastases followed. We considered that tumor cells spread through the patent processus vaginalis and grew at paratesticular space in hydrocele. One month after the end of 12 months of salvage chemotherapy and abdominal radiotherapy, the patient has no evidence of disease.
除肺、淋巴结和肝脏外，其他部位发生肾母细胞瘤（WT）转移并不常见。阴囊内转移极为罕见。我们报告一名3岁IIA期WT男孩，在腹部复发手术后2个月出现睾丸旁转移。初诊时他有右侧阴囊鞘膜积液。患者接受了右侧根治性睾丸切除术，病理检查显示为睾丸旁WT转移。随后出现了腹腔内和腹膜播散性转移。我们认为肿瘤细胞通过未闭的鞘突管扩散，并在鞘膜积液的睾丸旁间隙生长。在12个月的挽救性化疗和腹部放疗结束1个月后，患者无疾病证据。
