Kajbafzadeh Abdol-Mohammad, Javan-Farazmand Niloufar, Baghayee Arash, Hedayat Zeinab
Department of Urology, Paediatric Urology Research Center, Children's Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
J Pediatr Hematol Oncol. 2011 Dec;33(8):e347-9. doi: 10.1097/MPH.0b013e31821de586.
Testicular or paratesticular metastasis from Wilms tumor (WT) is extremely rare. We report a 5-year-old boy with WT of right kidney presented with metastasis to the ipsilateral spermatic cord. The patient underwent a high inguinal right orchiectomy. Histopathological examination revealed infiltration of WT to spermatic cord but the testis and epididymis were not involved. The patient received the standard chemotherapy regimen but the response to treatment was poor with 2 tumor recurrences within the follow-up period. Among the mechanisms of metastasis to scrotal region, retrograde venous and the patent processus vaginalis seem to be more common and also preventable.
肾母细胞瘤（WT）发生睾丸或睾丸旁转移极为罕见。我们报告一名5岁患有右肾WT的男孩出现同侧精索转移。该患者接受了高位右侧腹股沟睾丸切除术。组织病理学检查显示WT浸润至精索，但睾丸和附睾未受累。患者接受了标准化疗方案，但治疗反应不佳，随访期间出现2次肿瘤复发。在转移至阴囊区域的机制中，逆行静脉和未闭的鞘状突似乎更为常见且可预防。
