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脆性X综合征男性患者表达性语言中的语义缺陷。

Expressive semantic deficit in the productive language of males with fragile X syndrome.

作者信息

Sudhalter V, Maranion M, Brooks P

机构信息

New York State Institute for Basic Research in Developmental Disabilities, Staten Island 10314.

出版信息

Am J Med Genet. 1992;43(1-2):65-71. doi: 10.1002/ajmg.1320430110.

Abstract

Eleven males with fragile x syndrome [fra(X)] between the ages of 6 and 41, with an average communication age of 4 years 4 months and 11 normally developing 4 year old boys were administered a sentence completion task that assessed expressive semantic competence. The fra(X) males produced significantly more semantic errors than the normally developing 4 year children. Additionally, it was shown that sentences which could be correctly completed by a wider choice of words affected fra(X) males more than the nondisabled children. These 2 results suggest that the expressive semantic system is an area of specific deficit in fra(X) males.

摘要

11名年龄在6岁至41岁之间的脆性X综合征[fra(X)]男性,平均交流年龄为4岁4个月,以及11名发育正常的4岁男孩接受了一项句子完成任务,该任务评估了表达性语义能力。与发育正常的4岁儿童相比,fra(X)男性产生的语义错误明显更多。此外,研究表明,能用更广泛的词汇正确完成的句子对fra(X)男性的影响比对非残疾儿童的影响更大。这两个结果表明,表达性语义系统是fra(X)男性特定的缺陷领域。

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