Thurman Angela John, McDuffie Andrea, Hagerman Randi J, Josol Cynde K, Abbeduto Leonard
MIND Institute, University of California Davis, 2825 50th Street, Room 2101, Davis, CA, 95817, USA.
Department of Psychiatry and Behavioral Sciences, University of California Davis, Davis, USA.
J Autism Dev Disord. 2017 Mar;47(3):728-743. doi: 10.1007/s10803-016-3003-2.
Despite the similarities observed between the fragile X syndrome (FXS) and autism spectrum disorder (ASD) phenotypes, few studies have compared their behavioral profiles outside of ASD symptomatology. In the present study, we sought to compare lexical and grammatical abilities in these two conditions. Comparisons of language abilities in both of these conditions are particularly interesting because both conditions are characterized by difficulties navigating social interactions. Results suggest that although both FXS and ASD are associated with language difficulties, there are important differences between the two conditions in terms of the language profiles observed and the factors influencing language when considering children of similar developmental levels. Theoretical implications are discussed.
尽管脆性X综合征（FXS）和自闭症谱系障碍（ASD）的表型之间存在相似之处，但很少有研究在ASD症状学之外比较它们的行为特征。在本研究中，我们试图比较这两种情况下的词汇和语法能力。对这两种情况下的语言能力进行比较特别有趣，因为这两种情况都以社交互动困难为特征。结果表明，虽然FXS和ASD都与语言困难有关，但在考虑发育水平相似的儿童时，这两种情况在观察到的语言特征以及影响语言的因素方面存在重要差异。本文讨论了其理论意义。
