[肝豆状核变性患者中凯泽-弗莱舍环的患病率]

[Prevalence of Kayser-Fleischer ring in patients with Wilson's disease].

作者信息

Oracz Grzegorz, Klimczak-Slaczka Dorota, Sokołowska-Oracz Anna, Socha Piotr, Grałek Mirosława, Szaflik Jerzy, Dadalski Maciej

机构信息

Z Kliniki Gastroenterologii, Hepatologii i Immunologii Instytutu-Pomnika Centrum Zdrowia Dziecka w Warszawie.

出版信息

Klin Oczna. 2005;107(1-3):54-6.

PMID:16052801

Abstract

The aim of the study was to assess prevalence of Kayser-Fleischer ring in children with Wilson's disease. 36 patients aged 7-17 years were enrolled into the study. All of them underwent ophthalmic examination by slit-lamp biomicroscopy. Kayser-Fleischer ring was found in 2 children (5.6%)--16 years old boy and girl with liver insufficiency. In addition, the girl had neurological symptoms. After 2 years of treatment K-F ring was not detected in the girl's eyes. Our data indicate that Kayser-Fleischer ring is rare in children and its absence does not exclude diagnosis of Wilson's disease.

摘要

该研究的目的是评估肝豆状核变性患儿凯-弗环的患病率。36名年龄在7至17岁的患者被纳入该研究。他们均接受了裂隙灯生物显微镜眼科检查。在2名儿童（5.6%）中发现了凯-弗环，分别是一名16岁患有肝功能不全的男孩和女孩。此外，该女孩有神经症状。经过2年治疗后，在该女孩眼中未检测到凯-弗环。我们的数据表明，凯-弗环在儿童中罕见，其不存在并不排除肝豆状核变性的诊断。