Grubor Nikica, Colović Radoje, Colović Natasa, Radak Vladimir
Institute of Digestive System Diseases, Clinical Centre of Serbia, Belgrade.
Srp Arh Celok Lek. 2005 Jan-Feb;133(1-2):46-51. doi: 10.2298/sarh0502046g.
Splenic abscess is a rare disease but with increasing frequency. The authors present 9 patients with splenic abscess treated at the Institute of Digestive System Diseases, Clinical Centre of Serbia, in a period from January 1, 1986 to May 15, 2004. Splenic abscess was the complication of septic endocarditis in 4, trauma in 2, dental infection in 1, while in 2 cases it was the complication of chemotherapy in myeloproliferative disorders. All 9 patients had fever, 7 - abdominal pain, 4 - left shoulder pain, and 1 patient had nausea and vomiting. Higher white blood count was found in 6 patients, pleural effusion in 4, elevated left hemidiaphragm in 1 and basal pneumonia in 1 patient as well. Ultrasonography and CT were the most reliable diagnostic procedures. CT was superior in diagnosis of multiple small abscesses. Culture of the pus recovered the Enterococcus in 3 cases, Streptococcus a hemolyticus in 1, Staphylococcus epidermidis and Candida albicans in 1, Staphylococcus aureus, E. Coil and Candida albicans in 1, Staphylococcus aureus i Salmonella enteritidis in 1 case. Eight patients underwent splenectomy and 1 was cured by combined antibiotics in high doses. One patient died postoperatively due to septic endocarditis that had been present before surgery. The authors believe that splenectomy and antibiotics administered according to drug susceptibility test as well as management of underlying disease are the method of choice for splenic abscess treatment. Conservative antibiotic treatment is indicated in selected cases only.
脾脓肿是一种罕见疾病,但发病率呈上升趋势。作者介绍了1986年1月1日至2004年5月15日期间在塞尔维亚临床中心消化系统疾病研究所接受治疗的9例脾脓肿患者。脾脓肿是4例感染性心内膜炎、2例创伤、1例牙科感染的并发症,而在2例中是骨髓增殖性疾病化疗的并发症。所有9例患者均有发热,7例有腹痛,4例有左肩痛,1例有恶心和呕吐。6例患者白细胞计数升高,4例有胸腔积液,1例左膈升高,1例有基底肺炎。超声检查和CT是最可靠的诊断方法。CT在诊断多发性小脓肿方面更具优势。脓液培养在3例中检出肠球菌,1例中检出甲型溶血性链球菌,1例中检出表皮葡萄球菌和白色念珠菌,1例中检出金黄色葡萄球菌、大肠杆菌和白色念珠菌,1例中检出金黄色葡萄球菌和肠炎沙门氏菌。8例患者接受了脾切除术,1例通过大剂量联合使用抗生素治愈。1例患者术后因术前已存在的感染性心内膜炎死亡。作者认为,脾切除术、根据药敏试验使用抗生素以及治疗基础疾病是脾脓肿治疗的首选方法。仅在选定病例中采用保守抗生素治疗。