Reaven Gerald M
Division of Cardiovascular Medicine, Falk CVRC, Stanford Medical Center, California 94305, USA.
Cell Metab. 2005 Jan;1(1):9-14. doi: 10.1016/j.cmet.2004.12.001.
Although the concept of Syndrome X was introduced in the Banting Medal address of 1988 (Reaven, 1988), the notion that led to its genesis had started approximately 50 years earlier. In this short history, an attempt will be made to trace the two paths of scientific discovery that were formally merged in New Orleans in 1988 to form the scientific foundation of Syndrome X. In addition, the developments in the last 16 years that have led from the notion of Syndrome X to the broader concept of an Insulin Resistance Syndrome (IRS) will be briefly summarized.
尽管X综合征的概念是在1988年的班廷奖章演讲中提出的（雷文，1988年），但其起源的观念大约在50年前就已开始。在这段简短的历史中，将尝试追溯两条科学发现的路径，这两条路径于1988年在新奥尔良正式合并，形成了X综合征的科学基础。此外，还将简要总结过去16年中从X综合征的概念发展到更广泛的胰岛素抵抗综合征（IRS）概念的情况。
