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一名中风后躁狂症患者的左额颞叶血流灌注过多

Left frontotemporal hyperperfusion in a patient with post-stroke mania.

作者信息

Mimura Masaru, Nakagome Kazuyuki, Hirashima Natsuko, Ishiwata Hiroshi, Kamijima Kunitoshi, Shinozuka Akira, Matsuda Hiroshi

机构信息

Department of Neuropsychiatry, Showa University School of Medicine, 1-5-8 Hatanodai, Tokyo 142-8666, Japan.

出版信息

Psychiatry Res. 2005 Aug 30;139(3):263-7. doi: 10.1016/j.pscychresns.2005.05.007.

Abstract

A 78-year-old housewife with major depression developed a right-sided infarction in the territory of the middle cerebral arteries, followed by acute post-stroke mania. Comparison between pre- and post-stroke SPECT scans demonstrated a unique pattern of left orbitofrontal hyperperfusion with extensive right frontal hypoperfusion. A functional imbalance between right and left orbitofrontal cortices may be important in mania.

摘要

一位患有重度抑郁症的78岁家庭主妇在大脑中动脉供血区域发生了右侧梗死,随后出现了急性卒中后躁狂症。卒中前后的单光子发射计算机断层扫描(SPECT)比较显示出一种独特的模式,即左侧眶额皮质血流灌注过多,同时右侧额叶广泛血流灌注不足。左右眶额皮质之间的功能失衡可能在躁狂症中起重要作用。

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