[阿昔洛韦纳入周围性麻痹治疗的研究。45例病例分析]

[The incorporation of acyclovir into the treatment of peripheral paralysis. A study of 45 cases].

作者信息

Ramos Macías A, de Miguel Martínez I, Martín Sánchez A M, Gómez González J L, Martín Galán A

机构信息

Servicio de ORL, Hospital Clínico Universitario de Salamanca.

出版信息

Acta Otorrinolaringol Esp. 1992 Mar-Apr;43(2):117-20.

PMID:1605959

Abstract

The relation between use of acyclovir and facial nerve palsy prognosis was studied. In a randomised study, steroids or steroids + acyclovir (oral doses for Bell's palsy, and intravenous doses for Ramsay Hunt's syndrome) were given to 45 patients with facial palsy. There was a significant reduction of sequelae in patients treated with acyclovir in the group of Ramsay Hunt's syndrome (n = 15) (p less than 0.05). There were no significant differences in the group of Bell's palsy (n = 30) (p greater than 0.05), treated with acyclovir compared with steroids.

摘要

研究了阿昔洛韦的使用与面神经麻痹预后之间的关系。在一项随机研究中，对45例面神经麻痹患者给予类固醇或类固醇+阿昔洛韦（贝尔麻痹采用口服剂量，拉姆齐·亨特综合征采用静脉剂量）。在拉姆齐·亨特综合征组（n = 15）中，接受阿昔洛韦治疗的患者后遗症显著减少（p<0.05）。在贝尔麻痹组（n = 30）中，与使用类固醇治疗相比，使用阿昔洛韦治疗无显著差异（p>0.05）。