Borzych Dagmara, Zurowska Aleksandra, Bałasz Irena, Sabiniewicz Robert, Ereciński Jan
Z Kliniki Nefrologii Dzieciecej, Akademii Medycznej w Gdańsku.
Wiad Lek. 2005;58 Suppl 1:55-7.
Cardiovascular disease remains the leading cause of morbidity and mortality in the chronic renal failure adult population. Recently it has been shown that also paediatric CRF patients are at high risk of cardiovascular complications. Recent research programs are looking into the initial stages of chronic renal insufficiency to assess the early predictors of cardiac or cardiovascular disease. In the present study we analyzed the prevalence of left ventricular hypertrophy (LVH) in predialysis paediatric population and the potential value of efficient antihypertensive treatment on regression of left ventricular mass. Forty-nine chronic renal failure patients, aged 2-19 years, had two echocardiographic evaluations: at the time of establishing CRF diagnosis and after 30 months of antihypertensive treatment. In this study LVH was defined as left ventricular mass index (LVMI) greater than 51 g/m2.7. At the baseline assessment LVH was found in 18 out of 49 children (63.2%). In the second echocardiographic study LVH was present in 7 (14.2%) children.
心血管疾病仍然是成年慢性肾衰竭患者发病和死亡的主要原因。最近研究表明，儿科慢性肾衰竭患者也有发生心血管并发症的高风险。近期的研究项目正在探究慢性肾功能不全的初始阶段，以评估心脏或心血管疾病的早期预测因素。在本研究中，我们分析了透析前儿科人群中左心室肥厚（LVH）的患病率以及有效降压治疗对左心室质量消退的潜在价值。49例年龄在2至19岁的慢性肾衰竭患者接受了两次超声心动图评估：在确立慢性肾衰竭诊断时以及降压治疗30个月后。在本研究中，左心室肥厚定义为左心室质量指数（LVMI）大于51 g/m².7。在基线评估时，49名儿童中有18名（63.2%）发现有左心室肥厚。在第二次超声心动图研究中，7名（14.2%）儿童存在左心室肥厚。
