Nesbitt Shawna D
The University of Texas Southwestern Medical Center, Dallas, TX 75390-8899, USA.
Curr Hypertens Rep. 2005 Aug;7(4):244-8. doi: 10.1007/s11906-005-0020-5.
The excess risk for hypertension in black Americans continues to be a major health concern. Although there is considerable information regarding these disease trends, many of the major underpinnings of the etiology of hypertension remain unclear. The excess mortality in blacks due to heart disease, renal failure, and stroke is clearly directly related to the excess burden of hypertension. Amid the recent findings about the pathophysiology of hypertension, some clear differences in the effects of overweight, salt sensitivity, and vascular biology emerge along ethnic lines. These differences may shed some light on the development of more effective treatment strategies. Based on our current knowledge, aggressive management of hypertension in blacks is critical. This review highlights what is known about various factors affecting hypertension and its treatment in black Americans.
美国黑人患高血压的额外风险仍然是一个主要的健康问题。尽管有大量关于这些疾病趋势的信息,但高血压病因的许多主要基础仍不清楚。黑人因心脏病、肾衰竭和中风导致的额外死亡率显然与高血压的额外负担直接相关。在最近关于高血压病理生理学的研究结果中,超重、盐敏感性和血管生物学的影响在不同种族之间出现了一些明显的差异。这些差异可能为制定更有效的治疗策略提供一些线索。根据我们目前的知识,积极管理黑人的高血压至关重要。这篇综述重点介绍了已知的影响美国黑人高血压及其治疗的各种因素。