Alberte A, Martínez-Sagarra J M, Estébanez M J, Pascual P P
Servicios de Microbiología, Hospital del Río Hortega, Valladolid.
Enferm Infecc Microbiol Clin. 1992 Apr;10(4):216-9.
We describe the results of eight patients with renal tuberculosis treated with rifampin, isoniazid and ofloxacin. Ofloxacin was given orally, 200 mg b.i.d. for 6 months. During the first three months, rifampin (600 mg/daily) and isoniazid (330 mg/daily) were added. All M. tuberculosis strains isolated were sensitive to ofloxacin (MIC 1 mg/l). Follow-up cultures turned to be negative rapidly (during the first month of therapy), and no untoward effects were recorded. All patients had a 12-months follow-up period, and all were clinically cured. The treatment used was well accepted by all patients.
我们描述了8例接受利福平、异烟肼和氧氟沙星治疗的肾结核患者的治疗结果。氧氟沙星口服给药,每日2次,每次200mg,疗程6个月。在前三个月期间,加用利福平(每日600mg)和异烟肼(每日330mg)。所有分离出的结核分枝杆菌菌株对氧氟沙星敏感(最低抑菌浓度为1mg/l)。随访培养结果迅速转阴(在治疗的第一个月内),且未记录到不良反应。所有患者均接受了12个月的随访,全部临床治愈。所有患者对所用治疗方法耐受性良好。