Carroll P B, Herskowitz R D, Goodman A D, Busch R S, Beaser R S
Department of Medicine Joslin Diabetes Center, Boston, Massachusetts.
Acta Paediatr. 1992 Apr;81(4):355-8. doi: 10.1111/j.1651-2227.1992.tb12243.x.
It is rare for young diabetic patients to develop severe complications in the first years of their disease. We describe three patients, aged 14-23 years who developed cataracts and severe retinopathy within one to five years of diagnosis of diabetes. During the same period, one patient developed peripheral neuropathy and a second severe autonomic neuropathy. Rapid development of chronic complications in these patients raises the possibility that there may be a subset of patients with unusual susceptibility to complications. We re-emphasize the need for vigilant monitoring for complications in young diabetic patients, even in the first few years of their disease. In particular, young patients with visual complaints should be evaluated carefully for evidence of treatable eye disease.
年轻糖尿病患者在患病的头几年很少发生严重并发症。我们描述了三名年龄在14至23岁之间的患者,他们在确诊糖尿病后的一至五年内出现了白内障和严重的视网膜病变。在同一时期,一名患者出现了周围神经病变,另一名患者出现了严重的自主神经病变。这些患者慢性并发症的快速发展增加了可能存在对并发症异常易感性的患者亚群的可能性。我们再次强调,即使在年轻糖尿病患者患病的最初几年,也需要对并发症进行密切监测。特别是,有视力问题主诉的年轻患者应仔细评估是否有可治疗眼病的迹象。