Androulakakis P A, Davaris P, Karayannis A, Michael V, Aghioutantis C
Department of Pediatric Urology, Aghia Sophia Children's Hospital, Athens, Greece.
Child Nephrol Urol. 1992;12(1):32-4.
Neoplasms originating from the transitional epithelium of the urinary bladder are rare in children. This paper examines the clinical, epidemiological and histopathological characteristics of 3 such cases. The patients were males aged 4, 8 and 14 years at the time of diagnosis. Total painless hematuria was the presenting symptom in all of them. There was no history of previous exposure to dyes or other chemicals, but 1 patient was a systematic cigarette smoker. All tumors were solitary, noninfiltrating, grade 1 neoplasms. Following their local resection, no recurrences were noted 3-8 years postoperatively. This review supports the contention that transitional cell neoplasms of the bladder are less aggressive in children and, therefore, their local management constitutes an adequate therapeutic approach.
起源于膀胱移行上皮的肿瘤在儿童中较为罕见。本文研究了3例此类病例的临床、流行病学和组织病理学特征。这3例患者在诊断时年龄分别为4岁、8岁和14岁,均为男性。所有患者的首发症状均为全程无痛性血尿。既往均无接触染料或其他化学物质的病史,但有1例患者有系统性吸烟史。所有肿瘤均为单发、无浸润的1级肿瘤。在进行局部切除术后,术后3 - 8年未见复发。本综述支持以下观点:膀胱移行细胞肿瘤在儿童中侵袭性较小,因此,局部治疗是一种充分的治疗方法。