Zhang C
Xinjiang Medical College, Wulumuqi.
Zhonghua Yu Fang Yi Xue Za Zhi. 1992 Jan;26(1):19-22.
The paper reports the results of research of hair in the endemic arsenism area where water with arsenic content is 0.58 mg/L in Kuitun district, Xinjiang. In the area of endemic arsenism, the content of hair arsenic with arsenism patients is higher than that of subjects without arsenism. Hair arsenic content among residents was also higher than those of control areas. The stretch and relative strength of hair of subjects living in the area of endemic arsenism were lower than those of the areas of control. The ultrastructure of hair surface has obvious pathologic changes by scanning electron microscope examination. By using a hygienic standard (the arsenic content of water being 0.03 mg/L) to improve the drinking water for two years, the content of hair arsenic has reduced, approaching 95% upper confidence limit for normal hair (1.5 micrograms/g). The stretch and relative strength of hair have distinctly increased. The ultrastructure of hair surface has returned to near normal. The results of our investigation show that we should pay attention to the latent harm to residents in the high-arsenic-content area. The authors consider that hair arsenic content, stretch and relative strength of hair are sensitive and objective indexes to monitor the effects of improving water quality in area of endemic arsenism.
本文报道了新疆奎屯地区水砷含量为0.58mg/L的地方性砷中毒病区头发的研究结果。在地方性砷中毒病区，砷中毒患者头发砷含量高于无砷中毒者。病区居民头发砷含量也高于对照区。生活在地方性砷中毒病区居民头发的拉伸度和相对强度低于对照区。扫描电镜检查发现头发表面超微结构有明显病理改变。采用卫生标准（水砷含量为0.03mg/L）改善饮用水两年后，头发砷含量降低，接近正常头发95%可信上限（1.5μg/g）。头发的拉伸度和相对强度明显增加。头发表面超微结构已恢复接近正常。调查结果表明，应关注高砷含量地区对居民的潜在危害。作者认为，头发砷含量、头发拉伸度和相对强度是监测地方性砷中毒病区水质改善效果的敏感和客观指标。
