Neill J S, Silverman J F
Department of Pathology and Laboratory Medicine, East Carolina University School of Medicine, Greenville, NC 27858-4394.
Diagn Cytopathol. 1992;8(3):272-7. doi: 10.1002/dc.2840080316.
Twenty cases of fine-needle aspiration (FNA) biopsy of mediastinal tumors with ultrastructural studies of the aspirated material were reviewed. The cases were classified according to the cytologic and ultrastructural diagnosis. A specimen insufficient for ultrastructural study was obtained in five cases (25%). Refinement of the cytologic diagnosis was made in three cases (15%) and good correlation between the initial cytologic impression and the ultrastructural studies was seen in the remaining cases (60%). Comparison of different sites of FNA biopsy revealed a higher rate of ultrastructural examination in the cases involving the mediastinum. Illustrative cases of the use of electron microscopy in FNA biopsies of mediastinal tumors are presented.
回顾了20例纵隔肿瘤细针穿刺（FNA）活检病例，并对吸出物进行了超微结构研究。根据细胞学和超微结构诊断对病例进行分类。5例（25%）获得的标本不足以进行超微结构研究。3例（15%）对细胞学诊断进行了细化，其余病例（60%）初始细胞学印象与超微结构研究之间具有良好的相关性。对不同部位FNA活检的比较显示，纵隔相关病例的超微结构检查率更高。文中展示了电子显微镜在纵隔肿瘤FNA活检中的典型病例。
