Butenandt O
Kinderklinik, Universität München.
Fortschr Med. 1992 Jan 30;110(3):31-2, 35-6.
The diagnosis of growth hormone deficiency is established on the basis of auxological and endocrinological studies. Without treatment, the final stature will be reduced; by way of treatment, administration of biosynthetic human growth hormone is required. Total and partial growth hormone deficiency can be distinguished, as also neurosecretory dysfunction of growth hormone secretion. Growth hormone can also be successfully administered to girls with the Ullrich-Turner syndrome, but the doses required are somewhat higher than in the case of growth hormone deficiency. Other forms of reduced stature might possibly benefit from growth hormone treatment, but the results of ongoing studies on this point must first be obtained.
生长激素缺乏症的诊断是基于体格学和内分泌学研究确立的。未经治疗，最终身高将会降低；通过治疗，则需要给予生物合成人生长激素。可以区分完全性和部分性生长激素缺乏症，以及生长激素分泌的神经分泌功能障碍。生长激素也可成功用于患有乌尔里希-特纳综合征的女孩，但所需剂量比生长激素缺乏症患者略高。其他形式的身材矮小可能会从生长激素治疗中获益，但必须首先获得关于这一点的正在进行的研究结果。
