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Growth hormone deficiency and growth hormone therapy in Ullrich-Turner-syndrome.

作者信息

Butenandt O

出版信息

Klin Wochenschr. 1980 Jan 15;58(2):99-101. doi: 10.1007/BF01477194.

DOI:10.1007/BF01477194
PMID:7366123
Abstract

In a girl with Ullrich-Turner-Syndrome (gonadal dysgenesis 45, XO) and growth hormone deficiency, 10 U of human growth hormone/m2 body surface area/week increased the growth rate from 2.0 to 4.1 cm/year. Doses of up to 36 U/m2/week did not improve the growth rate in 4 girls with Ullrich-Turner-Syndrome who had normal plasma growth hormone concentration and increation. We conclude that growth hormone therapy is unsuccessful in dwarfism in Ullrich-Turner-Syndrome and should be reserved for patients with proven growth hormone deficiency.

摘要

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