Morillo-Leco G, Alcaraz-Rousselet M A, Díaz-Borrego P, Sáenz-Ramírez L, Artime C, Labarta-Bertol C
Servicio de Rehabilitación, Hospital Nacional de Parapléjicos, Toledo, Spain.
Rev Neurol. 2005;41(4):205-8.
Infections account for 3% of all non-traumatic spinal cord injuries. The demographic distribution and clinical course are still not fully understood in these patients.
The aim of this study was to determine the clinical-epidemiological characteristics and clinical course in patients with infectious spinal cord injury referred to our centre.
A retrospective study (over the period 1997-2003) was carried out. Variables examined included age, sex, type of injury, aetiology, causing agent, ASIA classification on admission and discharge.
N = 27 (8% of the total number of non-traumatic spinal cord injuries). Mean age: 37.3 years (range: 14-75). Higher prevalence was found between the ages of 20 and 39 years (48.1%) and in males (70.4%). A prevalence of dorsal injuries (59.3%) was also observed. On hospital admission most of the injuries were incomplete (70.4%) and this figure increased to 77.8% on discharge. Spondylodiscitis was the most frequent cause (51.9%) and Staphylococcus aureus was found to be the most common microbiological causing agent. The greatest prevalence of complete injuries was observed in cases of dorsal injuries (43.75%). All cases of tuberculosis were situated in the dorsal region (p < 0.05).
In our care centre, non-traumatic spinal cord injuries of an infectious origin seem to be most often caused by spondylodiscitis due to S. aureus, with a higher incidence in the dorsal region. They predominantly affect males in their thirties and forties, and usually give rise to incomplete injuries.
感染占所有非创伤性脊髓损伤的3%。这些患者的人口统计学分布和临床病程仍未完全明了。
本研究的目的是确定转诊至我们中心的感染性脊髓损伤患者的临床流行病学特征和临床病程。
开展了一项回顾性研究（时间段为1997年至2003年）。所检查的变量包括年龄、性别、损伤类型、病因、致病因子、入院及出院时的美国脊髓损伤协会（ASIA）分级。
N = 27例（占非创伤性脊髓损伤总数的8%）。平均年龄：37.3岁（范围：14 - 75岁）。20至39岁年龄段的患病率较高（48.1%），男性患病率较高（70.4%）。还观察到背部损伤的患病率较高（59.3%）。入院时大多数损伤为不完全性损伤（70.4%），出院时这一数字增至77.8%。脊椎椎间盘炎是最常见的病因（51.9%），金黄色葡萄球菌是最常见的微生物致病因子。在背部损伤病例中观察到完全性损伤的患病率最高（43.75%）。所有结核病例均位于背部区域（p < 0.05）。
在我们的护理中心，感染性非创伤性脊髓损伤似乎最常由金黄色葡萄球菌引起的脊椎椎间盘炎导致，背部区域发病率较高。它们主要影响三四十岁的男性，通常导致不完全性损伤。
