Zemtsovskiĭ M Iu, Kipriianov V S, Tros'ko O U, Brazhnikov A V, Strashnov V I
Anesteziol Reanimatol. 2005 May-Jun(3):11-5.
All accelerated opioid detoxifications under anesthesia, which were performed at our district hospital during 3 years (1999 to 2002), have been retrospectively analyzed. A total of 48 detoxifications were made in 43 patients. Three serious complications were recorded. In the first case, there was incomplete detoxification using naltrexone. The naloxone test was negative. After recovery from anesthesia, the patient developed a severe withdrawal syndrome that required repeated detoxification. In the second case, the patient developed bedsores at the site of the sacrum and scapulae after 7-hour detoxification. Reddening and edema disappeared on day 3 without treatment. In the third case, there was insufficient artificial ventilation due to inspiratory valvular defect. Capnography was not applied. The symptoms of hypercapnia, such hypertension, hyperemia, sweating, were regarded as the symptoms of abstinence so anesthesia was intensified. Valvular defect was detected when the patient developed hypoxia. All the patients were discharged from hospital in a satisfactory condition.
对我院区医院在3年期间（1999年至2002年）进行的所有麻醉下加速阿片类药物脱毒治疗进行了回顾性分析。43例患者共进行了48次脱毒治疗。记录到3例严重并发症。第一例中，使用纳曲酮进行脱毒不完全。纳洛酮试验呈阴性。麻醉恢复后，患者出现严重戒断综合征，需要再次进行脱毒治疗。第二例中，患者在7小时脱毒治疗后，骶骨和肩胛骨部位出现褥疮。未经治疗，第3天发红和水肿消失。第三例中，由于吸气瓣膜缺陷导致人工通气不足。未应用二氧化碳监测。高碳酸血症的症状，如高血压、充血、出汗，被视为戒断症状，因此加强了麻醉。当患者出现缺氧时发现瓣膜缺陷。所有患者均康复出院。
