Ginde Samir R, Geliebter Allan, Rubiano Frederick, Silva Analiza M, Wang Jack, Heshka Stanley, Heymsfield Steven B
Weight Control Unit, 1090 Amsterdam Avenue, 14th Floor, New York, NY 10025, USA.
Obes Res. 2005 Jul;13(7):1232-7. doi: 10.1038/oby.2005.146.
Patients with moderate and severe obesity, because of their physical size, often cannot be evaluated with conventional body composition measurement systems. The BOD POD air displacement plethysmography (ADP) system can accommodate a large body volume and may provide an opportunity for measuring body density (D(b)) in obese subjects. D(b) can be used in two- or three-compartment body composition models for estimating total body fat in patients with severe obesity. The purpose of this study was to compare D(b) measured by ADP to D(b) measured by underwater weighing (UWW) in subjects ranging from normal weight to severely obese.
D(b) was measured with UWW and BOD POD in 123 subjects (89 men and 34 women; age, 46.5 +/- 16.9 years; BMI, 31.5 +/- 7.3 kg/m2); 15, 70, and 10 subjects were overweight (25 < or = BMI < 30 kg/m2), obese (30 < or = BMI < 40 kg/m2), and severely obese (BMI > or = 40 kg/m2), respectively.
There was a strong correlation between D(b) (kilograms per liter) measured by UWW and ADP (r = 0.94, standard error of the estimate = 0.0073 kg/L, p < 0.001). Similarly, percent fat estimates from UWW and ADP using the two-compartment Siri equation were highly correlated (r = 0.94, standard error of the estimate = 3.58%, p < 0.001). Bland-Altman analysis showed no significant bias between D(b) measured by UWW and ADP. After controlling for D(b) measured by ADP, no additional between-subject variation in D(b) by UWW was accounted for by subject age, sex, or BMI.
Body density, an important physical property used in human body composition models, can be accurately measured by ADP in overweight and obese subjects.
中重度肥胖患者因其体型原因，常无法使用传统身体成分测量系统进行评估。BOD POD空气置换体积描记法（ADP）系统能够容纳较大的身体体积，可能为测量肥胖受试者的身体密度（D(b)）提供机会。D(b)可用于二室或三室身体成分模型，以估算重度肥胖患者的全身脂肪。本研究的目的是比较正常体重至重度肥胖受试者中，ADP测量的D(b)与水下称重（UWW）测量的D(b)。
对123名受试者（89名男性和34名女性；年龄，46.5±16.9岁；BMI，31.5±7.3kg/m2）进行UWW和BOD POD测量D(b)；其中超重（25≤BMI＜30kg/m2）、肥胖（30≤BMI＜40kg/m2）和重度肥胖（BMI≥40kg/m2）的受试者分别为15名、70名和10名。
UWW测量的D(b)（千克/升）与ADP测量的D(b)之间存在强相关性（r = 0.94，估计标准误差 = 0.0073kg/L，p＜0.001）。同样，使用二室Siri方程从UWW和ADP估算的体脂百分比高度相关（r = 0.94，估计标准误差 = 3.58%，p＜0.001）。Bland-Altman分析显示，UWW和ADP测量的D(b)之间无显著偏差。在控制ADP测量的D(b)后，UWW测量的D(b)在受试者年龄、性别或BMI方面无额外的受试者间差异。
身体密度是人体成分模型中使用的一项重要物理特性，ADP可在超重和肥胖受试者中准确测量。
