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SecD和SecF的第一个大的周质环在SecDF发挥功能方面起着重要作用。

The large first periplasmic loop of SecD and SecF plays an important role in SecDF functioning.

作者信息

Nouwen Nico, Piwowarek Magdalena, Berrelkamp Greetje, Driessen Arnold J M

机构信息

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

出版信息

J Bacteriol. 2005 Aug;187(16):5857-60. doi: 10.1128/JB.187.16.5857-5860.2005.

Abstract

A remarkable feature of proteins of the SecD and SecF family involved in protein translocation is that they possess a very large first periplasmic domain. Here we report that this large first periplasmic domain is not required for the SecD-SecF interaction but that it is important for catalyzing protein translocation.

摘要

参与蛋白质转运的SecD和SecF家族蛋白质的一个显著特征是它们拥有一个非常大的第一个周质结构域。我们在此报告,SecD与SecF相互作用并不需要这个大的第一个周质结构域,但它对催化蛋白质转运很重要。

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