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开胸术后持续输注局部麻醉药可改善疼痛管理效果。

Improved pain management outcomes with continuous infusion of a local anesthetic after thoracotomy.

作者信息

Wheatley Grayson H, Rosenbaum David H, Paul Michelle C, Dine Alan P, Wait Michael A, Meyer Dan M, Jessen Michael E, Ring W Steves, DiMaio J Michael

机构信息

Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

出版信息

J Thorac Cardiovasc Surg. 2005 Aug;130(2):464-8. doi: 10.1016/j.jtcvs.2005.02.011.

Abstract

OBJECTIVE

We sought to determine the effectiveness of an incisional infusion of local anesthetics through a continuous-infusion elastomeric pump for the management of postoperative pain after thoracotomy.

METHODS

We performed a retrospective comparative analysis of 110 patients undergoing thoracotomies between November 1999 and March 2003. Postoperative pain management with a continuous-infusion elastomeric pump providing local anesthetic into the incisional area was compared with a single-shot epidural in combination with continuous local anesthetic infusion and continuous thoracic epidural infusion. Data sources were reviewed for mean narcotic use, pain score, and complications.

RESULTS

After thoracotomy procedures, 38 patients received the ON-Q Pain Relief System (I-Flow Corp, Lake Forest, Calif), 32 received the ON-Q device and single-shot epidural infusion, and 40 received continuous epidural infusion. Demographic attributes, including age, body mass index, and sex were similar between the groups. Preoperative American Society of Anesthesiologists status was significantly higher in the ON-Q group compared with that in the other groups (P = .02). Narcotic use and pain scores were significantly reduced in the ON-Q group compared with that in the epidural group at all time points (P < .001). There were no wound-healing complications or infections associated with the use of the pump.

CONCLUSION

A continuous infusion of 0.25% bupivacaine at 4 mL/h through the ON-Q elastomeric infusion pump is a safe and effective adjunct in postoperative pain management after thoracotomy. The use of the ON-Q Pain Relief System results in decreased narcotic use and lower pain scores compared with continuous epidural infusion.

摘要

目的

我们试图确定通过持续输注弹性泵在开胸术后切口局部注入局部麻醉药来管理术后疼痛的有效性。

方法

我们对1999年11月至2003年3月期间接受开胸手术的110例患者进行了回顾性比较分析。将通过持续输注弹性泵向切口区域提供局部麻醉药的术后疼痛管理方法与单次硬膜外麻醉联合持续局部麻醉药输注及持续胸段硬膜外输注进行比较。审查数据来源以获取平均麻醉药使用量、疼痛评分和并发症情况。

结果

开胸手术后,38例患者接受了ON-Q疼痛缓解系统(I-Flow公司,加利福尼亚州莱克福里斯特),32例接受了ON-Q装置和单次硬膜外输注,40例接受了持续硬膜外输注。各组之间的人口统计学特征,包括年龄、体重指数和性别相似。与其他组相比,ON-Q组术前美国麻醉医师协会状态显著更高(P = 0.02)。在所有时间点,ON-Q组的麻醉药使用量和疼痛评分均显著低于硬膜外组(P < 0.001)。使用该泵未出现伤口愈合并发症或感染。

结论

通过ON-Q弹性输注泵以4 mL/h的速度持续输注0.25%布比卡因是开胸术后疼痛管理中一种安全有效的辅助方法。与持续硬膜外输注相比,使用ON-Q疼痛缓解系统可减少麻醉药使用量并降低疼痛评分。

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