Benussi Stefano, Nascimbene Simona, Calori Giliola, Denti Paolo, Ziskind Zvi, Kassem Samer, La Canna Giovanni, Pappone Carlo, Alfieri Ottavio
Division of Cardiac Surgery, S Raffaele Univeristy Hospital, Milan, Italy.
J Thorac Cardiovasc Surg. 2005 Aug;130(2):491-7. doi: 10.1016/j.jtcvs.2005.01.009.
When used for epicardial ablation, unipolar devices do not predictably yield transmural scars. Bipolar radiofrequency proved highly effective on the animal model, but clinical experience is still initial. We describe acute electrophysiologic findings and follow-up results of epicardial ablation with a novel bipolar radiofrequency device.
A bipolar ablator was used to perform a simplified left atrial lesion set in 90 consecutive patients with atrial fibrillation undergoing open heart surgery. Pacing thresholds were assessed during surgery to validate 24 pulmonary vein encircling lines (12 patients). Follow-up was 100% complete.
In 67 of 90 patients (84%), mitral valve disease was the main indication to surgery. Atrial fibrillation was continuous in 74 patients (82%) and intermittent in 16 patients (18%). Pacing threshold assessment showed a complete conduction block in 22 of 24 pulmonary vein couples (92%) after a single ablation and in all patients after doubling of the encircling lines. No complications related to the ablation procedure were recorded. The sinus rhythm restoration rate was 79% at 3 months, 87% at 6 months, and 89% (17/18 patients) at 1 year. Postablation organized arrhythmias consisted in right atrial flutter in 2 patients (2%) and left atrial flutter in 6 patients (7%).
Epicardial ablation with bipolar radiofrequency grants acute transmurality. A simplified lesion set proved highly effective in eliminating atrial fibrillation at 1-year follow-up. Our data suggest that addition of a lesion to the mitral annulus is advisable to prevent left atrial flutter.
用于心外膜消融时,单极设备无法可靠地产生透壁瘢痕。双极射频在动物模型中已证明非常有效,但临床经验仍处于初始阶段。我们描述了使用新型双极射频设备进行心外膜消融的急性电生理结果和随访结果。
使用双极消融器对90例连续接受心脏直视手术的房颤患者进行简化的左心房损伤组消融。在手术期间评估起搏阈值以验证24条肺静脉环绕线(12例患者)。随访率为100%。
90例患者中有67例(84%),二尖瓣疾病是手术的主要指征。74例患者(82%)房颤为持续性,16例患者(18%)为间歇性。起搏阈值评估显示,单次消融后24对肺静脉中有22对(92%)出现完全性传导阻滞,在环绕线加倍后所有患者均出现完全性传导阻滞。未记录到与消融手术相关的并发症。3个月时窦性心律恢复率为79%,6个月时为87%,1年时为89%(17/18例患者)。消融后有组织的心律失常包括2例患者(2%)出现右心房扑动和6例患者(7%)出现左心房扑动。
双极射频心外膜消融可实现急性透壁性。在1年的随访中,简化的损伤组被证明在消除房颤方面非常有效。我们的数据表明,建议在二尖瓣环处增加一个损伤以预防左心房扑动。