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采用双极射频进行完全性左心房消融。

Complete left atrial ablation with bipolar radiofrequency.

作者信息

Benussi Stefano, Nascimbene Simona, Galanti Andrea, Fumero Andrea, Dorigo Enrica, Zerbi Valerio, Cioni Micaela, Alfieri Ottavio

机构信息

Division of Cardiac Surgery, S Raffaele University Hospital, via Olgettina 60, 20132 Milan, Italy.

出版信息

Eur J Cardiothorac Surg. 2008 Apr;33(4):590-5. doi: 10.1016/j.ejcts.2008.01.005. Epub 2008 Feb 19.

Abstract

OBJECTIVE

Despite its efficacy and swiftness, bipolar radiofrequency is generally not used on the left isthmus for concern of injuring a coronary branch. Incomplete lesion sets or use of an additional unipolar device are often considered. We report a technique to perform a full left lesion set involving the mitral line using a standard bipolar radiofrequency device.

METHODS

An innovative complete left atrial lesion set was performed using only bipolar radiofrequency in 70 consecutive patients (study group). In 67/70 patients (96%) mitral valve disease was the main indication to surgery. Atrial fibrillation was permanent in 42 patients (60%), persistent in 25 (36%) and paroxysmal in three patients (4%). After beating-heart pulmonary vein isolation on-pump, the coronary-free area of the AV groove was marked epicardially by sticking a needle into the left atrial wall, behind the coronary sinus. The projection of the needle marker on the mitral annulus was then identified through the atriotomy and an endo-epicardial ablation was performed with the bipolar device involving the atrial wall, the coronary sinus, up to the annulus. The lesion set was then completed by connecting the encirclings and the left appendage, which was then sutured. Follow-up was 100% complete. Results were compared with those of a control group of 33 patients receiving bipolar radiofrequency left atrial ablations and a mitral connecting line with a second unipolar device.

RESULTS

All patients survived. No major complication occurred. Haematoma of the AV groove was observed during retrograde cardioplegia in one case. No myocardial ischaemia or re-exploration for bleeding (median 325 cc, interquartile range 250-442) occurred. Two out of 70 patients required a permanent pacemaker for AV block. Freedom from atrial fibrillation was 84% (95% CI: 75%, 93%) at 6 months and 81% (95% CI: 70%, 93%) at 1 year. One patient had left flutter. Comparison with the control group did not show any difference in clinical outcomes, but revealed bipolar ablation to the mitral annulus to abate the per patient cost of the ablation devices (1245+/-50 euro vs 2403+/-17 euro; p<0.0001).

CONCLUSIONS

Performing the mitral line with bipolar radiofrequency is safe and cost-effective. A complete left atrial ablation with a single bipolar radiofrequency device yields excellent clinical mid-term results.

摘要

目的

尽管双极射频消融术具有有效性和快速性,但由于担心损伤冠状动脉分支,一般不在左峡部使用。通常会考虑采用不完全消融线或使用额外的单极设备。我们报告一种使用标准双极射频设备完成包括二尖瓣线在内的完整左心房消融线的技术。

方法

连续70例患者(研究组)仅使用双极射频消融术进行了创新性的完整左心房消融。70例患者中有67例(96%)二尖瓣疾病是手术的主要适应证。42例患者(60%)为永久性房颤,25例(36%)为持续性房颤,3例(4%)为阵发性房颤。在体外循环心脏跳动下进行肺静脉隔离后,通过将针插入冠状窦后方的左心房壁,在心外膜标记房室沟的无冠状动脉区域。然后通过心房切口确定针标记在二尖瓣环上的投影,并用双极设备进行心内膜-心外膜消融,包括心房壁、冠状窦直至二尖瓣环。然后通过连接环绕线和左心耳完成消融线,随后对左心耳进行缝合。随访率达100%。将结果与33例接受双极射频左心房消融并使用第二个单极设备连接二尖瓣线的对照组患者的结果进行比较。

结果

所有患者均存活。未发生重大并发症。1例患者在逆行心脏停搏期间观察到房室沟血肿。未发生心肌缺血或再次开胸止血(中位数325 cc,四分位数间距250 - 442)。70例患者中有2例因房室传导阻滞需要植入永久性起搏器。6个月时房颤复发率为84%(95%可信区间:75%,93%),1年时为81%(95%可信区间:70%,93%)。1例患者发生左房扑动。与对照组相比,临床结果无差异,但显示对二尖瓣环进行双极消融可降低每名患者的消融设备成本(1245±50欧元对2403±17欧元;p<0.0001)。

结论

使用双极射频进行二尖瓣线消融是安全且具有成本效益的。使用单个双极射频设备进行完整的左心房消融可产生优异的中期临床结果。

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