[克拉斯诺达尔边疆区亚热带地区自然汉坦病毒感染疫源地的流行病学和病毒学特征]

[The epizootological and virological characteristics of a natural hantavirus infection focus in the subtropic zone of the Krasnodarsk Territory].

作者信息

Tkachenko E A, Okulova N M, Iunicheva Iu V, Morzunov S P, Khaĭbulina S F, Riabova T E, Vasilenko L E, Bashkirtsev V N, Dzagurova T K, Gorbachkova E A, Sedova N S, Balakirev A E, Dekonenko A E, Drozdov S G

出版信息

Vopr Virusol. 2005 May-Jun;50(3):14-9.

PMID:16078428

Abstract

A natural focus of hantavirus infection was detected and examined during the studies conducted in 2000-2002 around the Sochi (the western spurs of the Great Caucasus Ridge, which descended to the Black Sea (the Krasnodar Territory of Russia). At least 4 rodent species, such as Microtus majori, A. (S.) ponticus, A. agrarius, A. (S.) ciscaucasicus, were shown to participate in the circulation of hantaviruses. A comparative analysis of the nucleotide sequences of genomic S- and M-segments of hantaviruses has provided evidence that 13 viral RNA isolates from the A. (S.) ciscaucasicus belong to the Dobrava/Belgrade virus clade; however the RNA isolate from the Microtus majori belong to the Tula virus clade.

摘要

2000年至2002年期间，在索契周边地区（大高加索山脉西支，其延伸至黑海（俄罗斯克拉斯诺达尔边疆区））开展的研究中，检测并研究了汉坦病毒感染的一个自然疫源地。结果显示，至少有4种啮齿动物，如大姬鼠、 Ponticus田鼠、黑线姬鼠、Ciscaucasicus田鼠，参与了汉坦病毒的传播。对汉坦病毒基因组S和M片段核苷酸序列的比较分析表明，来自Ciscaucasicus田鼠的13个病毒RNA分离株属于多布拉伐/贝尔格莱德病毒分支；然而，来自大姬鼠的RNA分离株属于图拉病毒分支。