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[戊型病毒性肝炎。其研究问题]

[Viral hepatitis E. The problems of its study].

作者信息

Mikhaĭlov M I, Zamiatina N A, Poleshchuk V F

出版信息

Vopr Virusol. 2005 May-Jun;50(3):20-2.

PMID:16078429
Abstract

The paper presents the results of investigations of hepatitis E (HE), which have been made at the Department of Viral Hepatitides, M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides, Russian Academy of Medical Sciences. M. S. Balayan's discovery of hepatitis E virus permitted etiological interpretation of the cases of so-called non-A, non-B hepatitis with its fecal and oral transmission. The detection of antibodies to HE virus among different groups of the population of Russia (i.e. a hepatitis E nonendemic region of the world) suggests that they are frequently detected in the absence of disease notification. The fact that viral HE RNA has been detected in the pigs and wild boars inhabiting in the country is evidence in favor of an assumption that the virus is spread among these animals. The hypothesis for HE as a zoonosis is discussed in the paper.

摘要

本文介绍了俄罗斯医学科学院脊髓灰质炎和病毒性脑炎研究所病毒性肝炎部对戊型肝炎(HE)的研究结果。M.S.巴拉扬发现戊型肝炎病毒,使得对经粪口传播的所谓非甲非乙型肝炎病例有了病因学解释。在俄罗斯(即世界上戊型肝炎非流行地区)不同人群中检测到戊型肝炎病毒抗体,这表明在未报告疾病的情况下也经常检测到这些抗体。在该国的猪和野猪中检测到戊型肝炎病毒RNA这一事实,支持了该病毒在这些动物中传播的假设。本文讨论了戊型肝炎作为一种人畜共患病的假说。

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