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[混合性分枝杆菌感染问题——分枝杆菌病与结核病]

[The problem of mixed mycobacterial infections--mycobacteriosis and tuberculosis].

作者信息

Otten T F, Zaĭtsev A V, Solov'eva N S

出版信息

Probl Tuberk Bolezn Legk. 2005(6):58-62.

PMID:16078726
Abstract

Mycobacteriosis occurs in our country as sporadic cases; nevertheless the clinical significance of this disease is great since its course is severe and its treatment presents great difficulties. Eighteen patients with mycobacteriosis caused by M. avium (n = 14), M. malmoense (n = 2), M. kansasii (n = 1), and M. xenopi (n = 1) were followed up. Subsequently, all the examinees fell ill with tuberculosis due to nosocomial infection. The change of a pathogen was bacteriologically documented by the isolation of M. tuberculosis. Ten tuberculosis-infected persons died. In this connection, it is necessary to legislatively determine the status of mycobacteriosis as an independent entity, to develop a proposition on mycobacteriosis, including its diagnosis, treatment, and follow-up, as well as to enhance the knowledge of phthisiologists on how to manage patients with mycobacteriosis, and to improve the bacteriological diagnosis of the disease.

摘要

分枝杆菌病在我国以散发病例形式出现;然而,这种疾病的临床意义重大,因为其病程严重且治疗困难重重。对18例由鸟分枝杆菌(n = 14)、马尔默分枝杆菌(n = 2)、堪萨斯分枝杆菌(n = 1)和偶发分枝杆菌(n = 1)引起的分枝杆菌病患者进行了随访。随后,所有受检者因医院感染患上了结核病。通过分离结核分枝杆菌,从细菌学上记录了病原体的变化。10名结核病感染者死亡。鉴于此,有必要通过立法确定分枝杆菌病作为一个独立实体的地位,制定关于分枝杆菌病的提议,包括其诊断、治疗和随访,同时提高肺病学家对如何管理分枝杆菌病患者的认识,并改进该疾病的细菌学诊断。

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