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[早期梅毒脑膜炎所致颅神经功能丧失:一种战前综合征的再现]

[Loss of cranial-nerve function caused by early syphilitic meningitis: the comeback of a pre-war syndrome].

作者信息

Blok F A A, de Gans J, Schot L J, Mekkes J R, de Vries H J C

机构信息

Academisch Medisch Centrum/Universiteit van Amsterdam, Meibergdreefg, 1105 AZ, Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 2005 Jul 16;149(29):1636-40.

Abstract

Two men aged 39 and 38 who had had unprotected insertive and receptive anal sexual contact with men are presented: one had paralysis of the right half of his face and the other man had erythematous macules on the palms of his hands and the soles of his feet as well as partial alopecia, earache and progressive loss of hearing in his left ear. The latter one was also HIV-seropositive and on antiretroviral medication. Syphilitic meningitis was diagnosed in both men. The 2 patients recovered after being treated with intravenous benzyl penicillin. Syphilitic meningitis is a complication seen during the early stages of a syphilis infection. Since the introduction of penicillin it has become a rare disease. Early diagnosis is of importance since syphilitic meningitis has irreversible sequelae.

摘要

现报告两名分别为39岁和38岁的男性,他们与男性有过无保护的插入式和接受式肛交:其中一人右脸瘫痪,另一人手掌和脚底出现红斑性皮疹,伴有部分脱发、耳痛和左耳听力逐渐丧失。后者也是艾滋病毒血清阳性,并正在接受抗逆转录病毒药物治疗。两名男性均被诊断为梅毒脑膜炎。两名患者经静脉注射苄星青霉素治疗后康复。梅毒脑膜炎是梅毒感染早期出现的一种并发症。自青霉素问世以来,它已成为一种罕见疾病。早期诊断很重要,因为梅毒脑膜炎会有不可逆的后遗症。

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