Chitkara D K, Bredenoord A J, Wang M, Rucker M J, Talley N J
The Motility Unit, Division of Gastroenterology and Nutrition, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Neurogastroenterol Motil. 2005 Aug;17(4):518-22. doi: 10.1111/j.1365-2982.2005.00682.x.
The purpose of this study was to describe presenting symptoms, diagnostic testing, treatments and outcomes in a group of children with a diagnosis of aerophagia. A computerized diagnostic index was used to identify all children between the age of 1 and 17 years diagnosed with aerophagia at a tertiary care medical centre between 1975 and 2003. Individual medical charts were abstracted for information on the demographics, clinical features, co-morbid diagnoses, diagnostic work up and treatment of children with aerophagia. Information on presenting symptoms was also collected for a group of children who were retrospectively classified as having functional dyspepsia for comparison (n = 40). Forty-five children had a diagnosis of aerophagia. The mean duration of symptoms in children with aerophagia was 16 +/- 5 months. The most common gastrointestinal symptoms were abdominal pain, distention and frequent belching. Children with functional dyspepsia had a higher prevalence of nausea, vomiting, abdominal pain and unintentional weight loss compared to children with aerophagia (all P < 0.05). In conclusion, aerophagia is a disorder that is diagnosed in neurologically normal males and females, who can experience prolonged symptoms. Although many children with aerophagia present with upper gastrointestinal symptoms, the disorder appears to be distinct from functional dyspepsia.
本研究的目的是描述一组诊断为吞气症的儿童的症状表现、诊断检查、治疗及预后情况。利用计算机诊断索引，识别出1975年至2003年间在一家三级医疗中心诊断为吞气症的所有1至17岁儿童。提取了个体病历，以获取吞气症儿童的人口统计学信息、临床特征、共病诊断、诊断检查及治疗情况。还收集了一组经回顾性分类为功能性消化不良儿童（n = 40）的症状表现信息，用于比较。45名儿童被诊断为吞气症。吞气症儿童的症状平均持续时间为16±5个月。最常见的胃肠道症状为腹痛、腹胀和频繁嗳气。与吞气症儿童相比，功能性消化不良儿童恶心、呕吐、腹痛及非故意体重减轻的患病率更高（所有P < 0.05）。总之，吞气症是一种在神经功能正常的男性和女性中被诊断出的疾病，患者可能会经历较长时间的症状。虽然许多吞气症儿童表现出上消化道症状，但该疾病似乎与功能性消化不良不同。
