Halb C, Pomerleau M, Faure C
Division of Pediatric Gastroenterology, Department of Pediatrics, CHU Ste-Justine, Montréal, QC, Canada.
Neurogastroenterol Motil. 2014 Jul;26(7):1010-4. doi: 10.1111/nmo.12355. Epub 2014 May 5.
Childhood aerophagia is defined by the Rome III criteria as two or more of the following symptoms; air swallowing, abdominal distension due to intraluminal air, or repetitive belching and/or flatus. The aim of this study was to determine the multichannel intraesophageal impedance (MII) pattern in children suffering from aerophagia.
We compared the MII tracings of five children with aerophagia according to Rome III criteria (three girls, median age 7 years) to five controls (three girls, median age 8 years). Controls underwent MII for symptoms of gastro-esophageal reflux, and had normal findings. Liquid swallows (LS), air swallows (AS), mixed swallows (MS) and supragastric belching (SGB) were recorded. Meals were excluded from the analysis. All MII parameters were separately analyzed in the upright and recumbent position. All data are reported as median number of events per hour.
There was no difference in the total number of LS and MS between the two groups. However, the total number of AS in patients was significantly higher than in controls (26/h vs 5.5/h, p < 0.05) but only in the upright position (46/h vs 8.2 in control group, p < 0.05). SGB was noted only in patients with aerophagia (2.6/h vs 0/h, p < 0.01).
CONCLUSIONS & INFERENCES: Children suffering from aerophagia have a specific MII pattern with an increased frequency of air swallows in the upright position and supragastric belching. MII may be used as a tool to confirm diagnosis of aerophagia in children.
儿童吞气症根据罗马III标准定义为具有以下两种或更多症状：吞气、管腔内气体导致的腹胀、反复嗳气和/或排气。本研究的目的是确定患有吞气症儿童的多通道食管内阻抗（MII）模式。
我们将5名符合罗马III标准的吞气症儿童（3名女孩，中位年龄7岁）的MII描记图与5名对照儿童（3名女孩，中位年龄8岁）进行比较。对照组因胃食管反流症状接受MII检查，结果正常。记录液体吞咽（LS）、空气吞咽（AS）、混合吞咽（MS）和胃上嗳气（SGB）。分析中排除进餐情况。所有MII参数在直立位和卧位分别进行分析。所有数据报告为每小时事件的中位数。
两组之间LS和MS的总数无差异。然而，患者的AS总数显著高于对照组（26次/小时对5.5次/小时，p<0.05），但仅在直立位时如此（46次/小时对对照组的8.2次/小时，p<0.05）。仅在患有吞气症的患者中观察到胃上嗳气（2.6次/小时对0次/小时，p<0.01）。
患有吞气症的儿童具有特定的MII模式，在直立位时空气吞咽频率增加且出现胃上嗳气。MII可作为确诊儿童吞气症的一种工具。
