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表现为急性手部感染的Sweet综合征

Sweet's syndrome presenting as acute hand infection.

作者信息

O'Halloran Laura E, Bennett Laura L, Grothaus Peter C, Lynch Dennis J

机构信息

Division of Plastic Surgery, Scott & White Memorial Hospital and Clinic, Scott, Sherwood, and Brindley Foundation, Texas A&M University System Health Science Center College of Medicine, Temple, Texas, USA.

出版信息

Plast Reconstr Surg. 2005 Aug;116(2):497-501. doi: 10.1097/01.prs.0000172890.53979.09.

Abstract

BACKGROUND

Sweet's syndrome, originally described as an acute febrile neutrophilic dermatosis, belongs to a class of skin lesions that histologically have intense epidermal and/or dermal inflammatory infiltrate of neutrophils without evidence of infection or vasculitis. Skin lesions of Sweet's syndrome most commonly present on the face, trunk, upper extremities, and hands. The presenting lesions are often confused with infections because of their clinical appearance.

METHODS

A retrospective search of the electronic medical record was performed to identify patients with Sweet's syndrome from 1996 to the present. These records were then reviewed to identify those patients who had Sweet's syndrome that involved the hands.

RESULTS

A total of 103 patients with Sweet's syndrome have been seen and treated at Scott and White Memorial Hospital since 1996. Of these, 49 patients had lesions on the hands. The presentation, treatment, and outcomes of several of these patients are presented.

CONCLUSIONS

As physicians responsible for the treatment of hand lesions, it is important to consider the diagnosis of Sweet's syndrome because these wounds are unresponsive to antibiotics, do not benefit from débridement, and instead, require treatment with steroids.

摘要

背景

Sweet综合征最初被描述为急性发热性嗜中性皮病,属于一类皮肤病变,在组织学上有强烈的表皮和/或真皮嗜中性粒细胞炎性浸润,且无感染或血管炎证据。Sweet综合征的皮肤病变最常出现在面部、躯干、上肢和手部。由于其临床表现,这些病变常被误诊为感染。

方法

对电子病历进行回顾性检索,以确定1996年至今患有Sweet综合征的患者。然后对这些记录进行审查,以确定那些手部受累的Sweet综合征患者。

结果

自1996年以来,斯科特与怀特纪念医院共诊治了103例Sweet综合征患者。其中,49例患者手部有病变。本文介绍了其中几位患者的临床表现、治疗方法及治疗结果。

结论

作为负责治疗手部病变的医生,考虑Sweet综合征的诊断很重要,因为这些伤口对抗生素无反应,清创术无益,反而需要用类固醇进行治疗。

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