Turner E A, Thompson H D, Reddy C M, South M A, Garrett-Ellis B R, Mirkovic R R
Department of Pediatrics, Meharry Medical College, Nashville, Tennessee 37208.
J Natl Med Assoc. 1992 Jun;84(6):524-7.
The Committee on Infectious Diseases of the American Academy of Pediatrics, and the Advisory Committee on Immunization Practices of the Center for Disease Control for many years have recommended the routine use of influenza vaccine in various hemoglobinopathies including sickle cell disease. This recommendation, however, has not been included in the patient care protocols of the Comprehensive Sickle Cell Centers program of NIHLB. Most clinicians have not used yearly influenza vaccine for their patients with sickle cell disease. This article reports a case of a 5-year-old boy with sickle cell disease who had not received influenza vaccine. He developed pneumonitis and acute myositis during a serologically confirmed influenza B virus infection. The incapacitating and protracted course of his illness presented diagnostic and management problems. His case strongly supports the recommendation of the two infectious disease committees.
美国儿科学会传染病委员会以及疾病控制中心免疫实践咨询委员会多年来一直建议在包括镰状细胞病在内的各种血红蛋白病中常规使用流感疫苗。然而，这一建议并未被国立卫生研究院镰状细胞综合中心项目的患者护理方案所采纳。大多数临床医生并未为他们的镰状细胞病患者每年接种流感疫苗。本文报告了一例5岁患镰状细胞病且未接种流感疫苗的男孩。在血清学确诊的乙型流感病毒感染期间，他患上了肺炎和急性肌炎。其疾病导致身体衰弱且病程迁延，带来了诊断和治疗方面的问题。他的病例有力地支持了这两个传染病委员会的建议。
