Quesenberry Cherie D, Li Cuizhen, Chen Annette H, Zweizig Susan L, Ball Harrison G
Department of Obstetrics and Gynecology, University of Massachusetts Memorial Hospital, 119 Belmont Street, Worcester, MA 01605, USA.
Gynecol Oncol. 2005 Oct;99(1):218-21. doi: 10.1016/j.ygyno.2005.05.044.
There are 20 documented cases of primary ovarian angiosarcoma. Most patients present with metastatic disease and respond poorly to chemotherapy. There is little information available to counsel early-staged patients on the need for or efficacy of adjuvant chemotherapy.
We present a case of Stage Ic primary ovarian angiosarcoma treated with 3 cycles of adjuvant MAID chemotherapy. The patient is without evidence of disease 10 months post-operatively.
A review of the literature indicates a potential role for MAID chemotherapy in the treatment of ovarian angiosarcomas. Detection of Stage I disease appears to confer a better prognosis regardless of the utilization of adjuvant chemotherapy.
原发性卵巢血管肉瘤有20例文献记载的病例。大多数患者出现转移性疾病,对化疗反应不佳。几乎没有信息可用于为早期患者提供辅助化疗必要性或疗效的咨询。
我们报告一例Ic期原发性卵巢血管肉瘤患者,接受了3个周期的辅助MAID化疗。患者术后10个月无疾病证据。
文献回顾表明MAID化疗在卵巢血管肉瘤治疗中可能发挥作用。无论是否使用辅助化疗,I期疾病的检测似乎预示着更好的预后。