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聚腺苷酸核糖聚合酶抑制治疗卵巢血管肉瘤:一例报告并文献复习

Angiosarcoma of the ovary treated with polyadenosine ribose polymerase Inhibition, a case report and review of the literature.

作者信息

Johnson Andrea M, Argenta Peter A

机构信息

Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota, United States.

Division Gynecologic Oncology, Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN 55455, United States.

出版信息

Gynecol Oncol Rep. 2023 Aug 23;49:101264. doi: 10.1016/j.gore.2023.101264. eCollection 2023 Oct.

DOI:10.1016/j.gore.2023.101264
PMID:37680504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10481173/
Abstract

•Primary angiosarcoma of the ovary historically has no standard treatment due to its rarity, and outcomes have been variable.•Olaparib may represent a viable treatment option for primary angiosarcoma of the ovary with a somatic BRCA mutation.•Next-generation sequencing may play an important component in treatment of very rare cancers to guide new or uncommon therapies.

摘要

•由于卵巢原发性血管肉瘤罕见,历史上一直没有标准治疗方法,治疗结果也各不相同。

•奥拉帕尼可能是治疗伴有体细胞BRCA突变的卵巢原发性血管肉瘤的一种可行治疗选择。

•新一代测序可能在极罕见癌症的治疗中发挥重要作用,以指导新的或不常见的治疗方法。

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Portuguese Consensus Recommendations for Next-Generation Sequencing of Lung Cancer, Rare Tumors, and Cancers of Unknown Primary Origin in Clinical Practice.葡萄牙临床实践中肺癌、罕见肿瘤及原发灶不明癌症的下一代测序共识建议。
Acta Med Port. 2022 Sep 1;35(9):677-690. doi: 10.20344/amp.17680. Epub 2022 Jul 11.
2
Ovarian epithelioid angiosarcoma complicating pregnancy: a case report and review of the literature.卵巢上皮样血管肉瘤合并妊娠:病例报告及文献复习。
J Int Med Res. 2021 May;49(5):3000605211019641. doi: 10.1177/03000605211019641.
3
Primary ovarian angiosarcoma: a rare and recognizable ovarian tumor.原发性卵巢血管肉瘤:一种罕见且可识别的卵巢肿瘤。
J Ovarian Res. 2021 Jan 28;14(1):21. doi: 10.1186/s13048-021-00771-7.
4
Pediatric ovarian angiosarcoma treated with systemic chemotherapy and cytoreductive surgery with heated intraperitoneal chemotherapy: Case report and review of therapy.儿童卵巢血管肉瘤采用全身化疗和细胞减灭术联合腹腔内热化疗治疗:病例报告及治疗回顾。
Pediatr Blood Cancer. 2019 Jul;66(7):e27753. doi: 10.1002/pbc.27753. Epub 2019 Apr 11.
5
Trabectedin and olaparib in patients with advanced and non-resectable bone and soft-tissue sarcomas (TOMAS): an open-label, phase 1b study from the Italian Sarcoma Group.曲贝替定联合奥拉帕利治疗不可切除的晚期骨和软组织肉瘤患者(TOMAS):一项来自意大利肉瘤研究组的开放标签、1b 期研究
Lancet Oncol. 2018 Oct;19(10):1360-1371. doi: 10.1016/S1470-2045(18)30438-8. Epub 2018 Sep 11.
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