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CTX-M型超广谱β-内酰胺酶基因向不常见宿主的传播。

Dissemination of CTX-M-type extended-spectrum beta-lactamase genes to unusual hosts.

作者信息

Mugnaioli Claudia, Luzzaro Francesco, De Luca Filomena, Brigante Gioconda, Amicosante Gianfranco, Rossolini Gian Maria

机构信息

Dipartimento di Biologia Molecolare, Laboratorio di Fisiologia e Biotecnologia dei Microrganismi, Università di Siena, Policlinico Santa Maria alle Scotte, 53100 Siena, Italy.

出版信息

J Clin Microbiol. 2005 Aug;43(8):4183-5. doi: 10.1128/JCM.43.8.4183-4185.2005.

DOI:10.1128/JCM.43.8.4183-4185.2005
PMID:16081971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1233897/
Abstract

A Citrobacter amalonaticus and a Morganella morganii producing the CTX-M-1 extended-spectrum beta-lactamase (ESBL) were isolated from an area where this enzyme is now widespread in Escherichia coli. This is the first report of CTX-M-1 in the former species. In both cases the ESBL determinant was possibly acquired by these unusual hosts in vivo, after coinfection with E. coli strains carrying conjugative plasmids encoding CTX-M-1.

摘要

从一个CTX-M-1型超广谱β-内酰胺酶（ESBL）在大肠杆菌中广泛存在的地区分离出了一株无丙二酸柠檬酸杆菌和一株摩根摩根菌。这是首次在前一个菌种中发现CTX-M-1。在这两起案例中，ESBL决定簇可能是这些不常见的宿主在与携带编码CTX-M-1的接合质粒的大肠杆菌菌株共同感染后，于体内获得的。

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Detection of CTX-M-type beta-lactamase genes in fecal Escherichia coli isolates from healthy children in Bolivia and Peru.玻利维亚和秘鲁健康儿童粪便中分离出的大肠埃希菌中CTX-M型β-内酰胺酶基因的检测
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