耐环丙沙星的尿路致病性大肠杆菌分离株中致病因子的流行率降低。
Decreased prevalence of virulence factors among ciprofloxacin-resistant uropathogenic Escherichia coli isolates.
作者信息
Drews S J, Poutanen S M, Mazzulli T, McGeer A J, Sarabia A, Pong-Porter S, Rzayev Y, Willey B, Green K, Low D E
机构信息
Toronto Medical Laboratories and Mount Sinai Hospital, Toronto, Ontario, Canada, M5G 1X5.
出版信息
J Clin Microbiol. 2005 Aug;43(8):4218-20. doi: 10.1128/JCM.43.8.4218-4220.2005.
Abstract
Ciprofloxacin resistance was identified in 18% and 6% of consecutively collected, clinically significant urinary tract isolates of Escherichia coli from inpatients and outpatients, respectively. In comparison to ciprofloxacin-susceptible isolates, there were fewer resistant isolates that expressed beta-hemolysis (outpatient, 9% versus 87%, P < 0.0001; inpatient, 4% versus 76%, P < 0.0001) and that had a papEF genotype, genes encoding P fimbriae (outpatient, 30% versus 70%, P = 0.0004; inpatient, 26% versus 70%, P < 0.0001).
摘要
在分别从住院患者和门诊患者中连续收集的具有临床意义的大肠埃希菌尿路分离株中，环丙沙星耐药率分别为18%和6%。与环丙沙星敏感分离株相比，表达β溶血的耐药分离株较少（门诊患者中，9%对87%，P<0.0001；住院患者中，4%对76%，P<0.0001），且具有papEF基因型（编码P菌毛的基因）的耐药分离株也较少（门诊患者中，30%对70%，P = 0.0004；住院患者中，26%对70%，P<0.0001）。
相似文献
1
Decreased prevalence of virulence factors among ciprofloxacin-resistant uropathogenic Escherichia coli isolates.耐环丙沙星的尿路致病性大肠杆菌分离株中致病因子的流行率降低。
J Clin Microbiol. 2005 Aug;43(8):4218-20. doi: 10.1128/JCM.43.8.4218-4220.2005.
2
Are quinolone-resistant uropathogenic Escherichia coli less virulent?耐喹诺酮的尿路致病性大肠杆菌毒力更低吗？
J Infect Dis. 2002 Oct 1;186(7):1039-42. doi: 10.1086/342955. Epub 2002 Sep 13.
3
Virulence factors in Escherichia coli.大肠杆菌中的毒力因子。
J Clin Microbiol. 2005 Dec;43(12):6221; author reply 6221-2. doi: 10.1128/JCM.43.12.6221-6222.2005.
4
Prevalence of virulence factors and antimicrobial resistance of uropathogenic Escherichia coli in Jiangsu province (China).中国江苏省尿路致病性大肠杆菌的毒力因子流行情况及抗菌药物耐药性
Urology. 2009 Sep;74(3):702-7. doi: 10.1016/j.urology.2009.01.042. Epub 2009 Apr 10.
5
Chloramphenicol- and tetracycline-resistant uropathogenic Escherichia coli (UPEC) exhibit reduced virulence potential.对氯霉素和四环素耐药的尿路致病性大肠杆菌（UPEC）表现出较低的致病潜力。
Int J Antimicrob Agents. 2007 Nov;30(5):436-42. doi: 10.1016/j.ijantimicag.2007.06.025. Epub 2007 Aug 24.
6
Risk factors for ciprofloxacin resistance among Escherichia coli strains isolated from community-acquired urinary tract infections in Turkey.从土耳其社区获得性尿路感染中分离出的大肠杆菌菌株对环丙沙星耐药的危险因素。
J Antimicrob Chemother. 2005 Nov;56(5):914-8. doi: 10.1093/jac/dki344. Epub 2005 Sep 20.
7
Phylogenetic background and virulence genotype of ciprofloxacin-susceptible and ciprofloxacin-resistant Escherichia coli strains of human and avian origin.人类和禽类源对环丙沙星敏感及耐药的大肠杆菌菌株的系统发育背景和毒力基因型
J Infect Dis. 2009 Apr 15;199(8):1209-17. doi: 10.1086/597423.
8
Characteristics of Romanian fluoroquinolone-resistant human clinical Escherichia coli isolates.罗马尼亚耐氟喹诺酮类的人类临床大肠杆菌分离株的特征
Roum Arch Microbiol Immunol. 2008 Jan-Jun;67(1-2):23-9.
9
Emergence of ciprofloxacin resistance in Escherichia coli isolates from outpatient urine samples.门诊患者尿液样本中分离出的大肠杆菌对环丙沙星耐药性的出现。
Clin Microbiol Infect. 2007 Mar;13(3):328-31. doi: 10.1111/j.1469-0691.2006.01615.x.
10
Antimicrobial susceptibility of 136 Escherichia coli isolates from cases of neonatal meningitis and relationship with virulence.136株新生儿脑膜炎病例分离的大肠杆菌的药敏性及其与毒力的关系
Clin Microbiol Infect. 2007 Dec;13(12):1207-10. doi: 10.1111/j.1469-0691.2007.01838.x. Epub 2007 Oct 19.
引用本文的文献
1
Risk Factors for Recurrence of Community-Onset Urinary Tract Infections Caused by Extended-Spectrum Cephalosporin-Resistant Enterobacterales.产超广谱头孢菌素耐药肠杆菌科细菌引起的社区获得性尿路感染复发的危险因素
Open Forum Infect Dis. 2023 Nov 8;10(12):ofad561. doi: 10.1093/ofid/ofad561. eCollection 2023 Dec.
2
Metabolic and Morphotypic Trade-Offs within the Eco-Evolutionary Dynamics of Escherichia coli.大肠杆菌生态进化动力学中的代谢与形态权衡
Microbiol Spectr. 2022 Oct 26;10(5):e0067822. doi: 10.1128/spectrum.00678-22. Epub 2022 Sep 28.
3
In Vitro Reduction of Interleukin-8 Response to by Strains Isolated from the Same Polymicrobial Urines.从同一混合菌尿中分离出的菌株对白细胞介素-8反应的体外降低作用
Microorganisms. 2021 Jul 14;9(7):1501. doi: 10.3390/microorganisms9071501.
4
Poultry hatcheries as potential reservoirs for antimicrobial-resistant Escherichia coli: A risk to public health and food safety.家禽孵化场可能成为抗药性大肠杆菌的储存库：对公共卫生和食品安全的威胁。
Sci Rep. 2018 Apr 11;8(1):5859. doi: 10.1038/s41598-018-23962-7.
5
A study on the aac-(6)-lb-cr gene prevalence among ciprofloxacin-resistant strains of uropathogenic .一项关于耐环丙沙星的尿路致病性菌株中aac-(6)-lb-cr基因流行情况的研究。
Int J Appl Basic Med Res. 2016 Oct-Dec;6(4):258-261. doi: 10.4103/2229-516X.192603.
6
Susceptibility to β-lactams and quinolones of Enterobacteriaceae isolated from urinary tract infections in outpatients.门诊尿路感染分离出的肠杆菌科细菌对β-内酰胺类和喹诺酮类药物的敏感性
Braz J Microbiol. 2015 Oct-Dec;46(4):1155-9. doi: 10.1590/S1517-838246420140880. Epub 2015 Oct 9.
7
Global Phenotypic Characterization of Effects of Fluoroquinolone Resistance Selection on the Metabolic Activities and Drug Susceptibilities of Clostridium perfringens Strains.氟喹诺酮耐药性选择对产气荚膜梭菌菌株代谢活性和药敏性影响的全球表型特征分析
Int J Microbiol. 2014;2014:456979. doi: 10.1155/2014/456979. Epub 2014 Dec 21.
8
Molecular Characterization of Uropathogenic Escherichia coli: Nalidixic Acid and Ciprofloxacin Resistance, Virulent Factors and Phylogenetic Background.致病性大肠杆菌的分子特征：萘啶酸和环丙沙星耐药性、毒力因子及系统发育背景
J Clin Diagn Res. 2013 Dec;7(12):2727-31. doi: 10.7860/JCDR/2013/6613.3744. Epub 2013 Dec 15.
9
Comparative transcription analysis and toxin production of two fluoroquinolone-resistant mutants of Clostridium perfringens.对比分析两种耐氟喹诺酮的产气荚膜梭菌突变株的转录组和毒素产生情况。
BMC Microbiol. 2013 Mar 1;13:50. doi: 10.1186/1471-2180-13-50.
10
Urinary tract infection in a rural community of Nigeria.尼日利亚一个农村社区的尿路感染
N Am J Med Sci. 2011 Feb;3(2):75-7. doi: 10.4297/najms.2011.375.
本文引用的文献
1
Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa.降低铜绿假单胞菌中喹诺酮耐药性的适应性负担。
J Antimicrob Chemother. 2005 Jan;55(1):22-30. doi: 10.1093/jac/dkh505. Epub 2004 Dec 1.
2
Coupling DNA supercoiling to transcription in defined protein systems.在特定蛋白质系统中将DNA超螺旋与转录偶联起来。
J Biol Chem. 2004 Nov 12;279(46):47564-71. doi: 10.1074/jbc.M403798200. Epub 2004 Sep 1.
3
PapG-dependent adherence breaks mucosal inertia and triggers the innate host response.依赖于PapG的黏附打破黏膜惰性并触发宿主固有免疫反应。
J Infect Dis. 2004 May 1;189(9):1734-42. doi: 10.1086/383278. Epub 2004 Apr 14.
4
5
Non-hospital antimicrobial usage and resistance in community-acquired Escherichia coli urinary tract infection.社区获得性大肠埃希菌尿路感染中的非医院抗菌药物使用与耐药性
J Antimicrob Chemother. 2003 Dec;52(6):1005-10. doi: 10.1093/jac/dkg488. Epub 2003 Nov 12.
6
The role of bacterial virulence and host factors in patients with Escherichia coli bacteremia who have acute cholangitis or upper urinary tract infection.细菌毒力和宿主因素在患有急性胆管炎或上尿路感染的大肠杆菌菌血症患者中的作用。
Clin Infect Dis. 2002 Nov 15;35(10):1161-6. doi: 10.1086/343828. Epub 2002 Oct 28.
7
Identification of virulence genes in uropathogenic Escherichia coli by multiplex polymerase chain reaction and their association with infectivity in mice.通过多重聚合酶链反应鉴定尿路致病性大肠杆菌中的毒力基因及其与小鼠感染性的关联。
Urology. 2002 Sep;60(3):537-41. doi: 10.1016/s0090-4295(02)01766-1.
8
Are quinolone-resistant uropathogenic Escherichia coli less virulent?耐喹诺酮的尿路致病性大肠杆菌毒力更低吗？
J Infect Dis. 2002 Oct 1;186(7):1039-42. doi: 10.1086/342955. Epub 2002 Sep 13.
9
Evolutionary barriers to quinolone resistance in Streptococcus pneumoniae.肺炎链球菌对喹诺酮类药物耐药的进化障碍
Microb Drug Resist. 2002 Summer;8(2):79-84. doi: 10.1089/107662902760190617.
10
Virulence factors of uropathogens.尿路病原体的毒力因子。
Curr Opin Urol. 2002 Jan;12(1):33-8. doi: 10.1097/00042307-200201000-00007.
Zotero 插件