Drews S J, Poutanen S M, Mazzulli T, McGeer A J, Sarabia A, Pong-Porter S, Rzayev Y, Willey B, Green K, Low D E
Toronto Medical Laboratories and Mount Sinai Hospital, Toronto, Ontario, Canada, M5G 1X5.
J Clin Microbiol. 2005 Aug;43(8):4218-20. doi: 10.1128/JCM.43.8.4218-4220.2005.
Ciprofloxacin resistance was identified in 18% and 6% of consecutively collected, clinically significant urinary tract isolates of Escherichia coli from inpatients and outpatients, respectively. In comparison to ciprofloxacin-susceptible isolates, there were fewer resistant isolates that expressed beta-hemolysis (outpatient, 9% versus 87%, P < 0.0001; inpatient, 4% versus 76%, P < 0.0001) and that had a papEF genotype, genes encoding P fimbriae (outpatient, 30% versus 70%, P = 0.0004; inpatient, 26% versus 70%, P < 0.0001).
在分别从住院患者和门诊患者中连续收集的具有临床意义的大肠埃希菌尿路分离株中，环丙沙星耐药率分别为18%和6%。与环丙沙星敏感分离株相比，表达β溶血的耐药分离株较少（门诊患者中，9%对87%，P<0.0001；住院患者中，4%对76%，P<0.0001），且具有papEF基因型（编码P菌毛的基因）的耐药分离株也较少（门诊患者中，30%对70%，P = 0.0004；住院患者中，26%对70%，P<0.0001）。
