耐克林霉素的具核梭杆菌菌血症和褥疮感染。
Clindamycin-resistant Fusobacterium varium bacteremia and decubitus ulcer infection.
作者信息
Legaria M C, Lumelsky G, Rodriguez V, Rosetti S
机构信息
Hospital Gral de Agudos E. Tornú, Buenos Aires, Argentina.
出版信息
J Clin Microbiol. 2005 Aug;43(8):4293-5. doi: 10.1128/JCM.43.8.4293-4295.2005.
Abstract
Bacteremia due to Fusobacterium spp. is unusual (<10% of cases of anaerobic bacteremia), and the isolation of Fusobacterium varium is especially uncommon. The most probable sources of Fusobacterium bacteremia are the respiratory, the gastrointestinal, and the genitourinary tracts. A.-M. Bourgault et al. (Clin. Infect. Dis. 25[Suppl. 2]:181-183) described 40 patients with Fusobacterium bacteremia; only 3 had Fusobacterium varium, and no one had decubitus scars as the portal of entry. In another published series (S. Henry, A. De Maria, and W. R. McCabe, Am. J. Med. 75:225-231, 1983) of 26 cases, two patients had concomitant pulmonary lesions and decubitus ulcers but there was no identification to the species level mentioned. We report a case of Fusobacterium varium bacteremia and infected sacral decubitus ulcer in an elderly patient.
摘要
具核梭杆菌引起的菌血症并不常见（占厌氧菌血症病例的比例不到10%），而多变梭杆菌的分离尤为罕见。具核梭杆菌菌血症最可能的来源是呼吸道、胃肠道和泌尿生殖道。A.-M. 布尔高特等人（《临床传染病》25[增刊2]：181 - 183）描述了40例具核梭杆菌菌血症患者；只有3例感染的是多变梭杆菌，且无人以褥疮瘢痕作为感染入口。在另一个已发表的系列研究（S. 亨利、A. 德玛丽亚和W. R. 麦凯布，《美国医学杂志》75：225 - 231，1983）中，26例病例里有两名患者同时患有肺部病变和褥疮溃疡，但未提及具体的菌种鉴定情况。我们报告一例老年患者发生多变梭杆菌菌血症并伴有骶部褥疮溃疡感染的病例。
相似文献
1
Clindamycin-resistant Fusobacterium varium bacteremia and decubitus ulcer infection.耐克林霉素的具核梭杆菌菌血症和褥疮感染。
J Clin Microbiol. 2005 Aug;43(8):4293-5. doi: 10.1128/JCM.43.8.4293-4295.2005.
2
Epidemiological characteristics of infections caused by Bacteroides, Prevotella and Fusobacterium species: a prospective observational study.拟杆菌属、普雷沃菌属和梭杆菌属引起感染的流行病学特征：一项前瞻性观察研究。
Anaerobe. 2011 Jun;17(3):113-7. doi: 10.1016/j.anaerobe.2011.05.013. Epub 2011 Jun 2.
3
Febrile neutropenia and Fusobacterium bacteremia: clinical experience with 13 cases.
Support Care Cancer. 2003 May;11(5):332-5. doi: 10.1007/s00520-003-0452-x. Epub 2003 Mar 13.
4
Rare isolation of Fusobacterium varium from a case of Fournier's gangrene.罕见的福赛斯坦纳菌从一例 Fournier 坏疽中分离出来。
Anaerobe. 2019 Jun;57:82-85. doi: 10.1016/j.anaerobe.2019.03.020. Epub 2019 Apr 2.
5
Fusobacterium bloodstream infections: A literature review and hospital-based case series.梭杆菌血流感染：文献复习和基于医院的病例系列。
Anaerobe. 2020 Apr;62:102165. doi: 10.1016/j.anaerobe.2020.102165. Epub 2020 Jan 28.
6
Fusobacterium bacteremia: clinical significance and outcomes.梭杆菌菌血症：临床意义和结局。
J Microbiol Immunol Infect. 2009 Aug;42(4):336-42.
7
Postpartum Fusobacterium gonidiaformans bacteremia.产后芽生梭菌菌血症。
Anaerobe. 2020 Apr;62:102168. doi: 10.1016/j.anaerobe.2020.102168. Epub 2020 Jan 28.
8
Bacteremia associated with decubitus ulcers.与压疮相关的菌血症。
Arch Intern Med. 1983 Nov;143(11):2093-5.
9
Incidence, risk factors, and outcomes of Fusobacterium species bacteremia.梭杆菌属菌血症的发生率、危险因素和结局。
BMC Infect Dis. 2013 Jun 5;13:264. doi: 10.1186/1471-2334-13-264.
10
Characterization of Fusobacterium isolates from the respiratory tract of white-tailed deer (Odocoileus virginianus).从白尾鹿（弗吉尼亚鹿）呼吸道分离出的梭杆菌菌株的特性分析。
J Vet Diagn Invest. 2014 Mar;26(2):213-20. doi: 10.1177/1040638714523613. Epub 2014 Mar 3.
引用本文的文献
1
Fusobacterium varium in cattle: prevalence and concentrations in healthy livers, liver abscesses, and ruminal and colonic epithelial tissues.牛体内的具核梭杆菌：在健康肝脏、肝脓肿以及瘤胃和结肠上皮组织中的流行情况与浓度
J Anim Sci. 2025 Jan 4;103. doi: 10.1093/jas/skaf194.
2
Risk of mortality in Fusobacterium species bloodstream infection from a large Australian cohort.来自澳大利亚一个大型队列的具核梭杆菌血流感染的死亡风险。
Eur J Clin Microbiol Infect Dis. 2025 Feb;44(2):427-436. doi: 10.1007/s10096-024-05012-5. Epub 2024 Dec 18.
3
Increasing Fusobacterium infections with Fusobacterium varium, an emerging pathogen.由新出现的病原体多变梭杆菌引起的梭杆菌感染不断增加。
PLoS One. 2022 Apr 14;17(4):e0266610. doi: 10.1371/journal.pone.0266610. eCollection 2022.
4
Pancreatic Diseases and Microbiota: A Literature Review and Future Perspectives.胰腺疾病与微生物群：文献综述及未来展望
J Clin Med. 2020 Nov 1;9(11):3535. doi: 10.3390/jcm9113535.
5
Gut microbiome in type 1 diabetes: A comprehensive review.1 型糖尿病中的肠道微生物组：全面综述。
Diabetes Metab Res Rev. 2018 Oct;34(7):e3043. doi: 10.1002/dmrr.3043. Epub 2018 Jul 17.
6
Bacteremia associated with pressure ulcers: a prospective cohort study.压疮相关菌血症：一项前瞻性队列研究。
Eur J Clin Microbiol Infect Dis. 2018 May;37(5):969-975. doi: 10.1007/s10096-018-3216-8. Epub 2018 Feb 26.
7
Differences in the gut microbiota of dogs () fed a natural diet or a commercial feed revealed by the Illumina MiSeq platform.通过Illumina MiSeq平台揭示的食用天然饮食或商业饲料的犬类肠道微生物群差异。
Gut Pathog. 2017 Nov 21;9:68. doi: 10.1186/s13099-017-0218-5. eCollection 2017.
8
Microbial antigen mimics activate diabetogenic CD8 T cells in NOD mice.微生物抗原模拟物激活非肥胖糖尿病（NOD）小鼠中的致糖尿病CD8 T细胞。
J Exp Med. 2016 Sep 19;213(10):2129-46. doi: 10.1084/jem.20160526. Epub 2016 Sep 12.
9
Fusobacterium species infections: clinical spectrum and outcomes at a district general hospital.梭杆菌属感染：一家区综合医院的临床谱及结局
Infection. 2014 Apr;42(2):363-70. doi: 10.1007/s15010-013-0564-2. Epub 2013 Dec 11.
本文引用的文献
1
Induction of experimental ulcerative colitis by Fusobacterium varium isolated from colonic mucosa of patients with ulcerative colitis.从溃疡性结肠炎患者结肠黏膜分离出的具核梭杆菌诱导实验性溃疡性结肠炎
Gut. 2003 Jan;52(1):79-83. doi: 10.1136/gut.52.1.79.
2
Update on the taxonomy and clinical aspects of the genus fusobacterium.梭杆菌属分类学及临床方面的最新进展。
Clin Infect Dis. 2002 Sep 1;35(Suppl 1):S22-7. doi: 10.1086/341916.
3
Fusobacterium varium localized in the colonic mucosa of patients with ulcerative colitis stimulates species-specific antibody.定位于溃疡性结肠炎患者结肠黏膜中的具核梭杆菌可刺激产生种特异性抗体。
J Gastroenterol Hepatol. 2002 Aug;17(8):849-53. doi: 10.1046/j.1440-1746.2002.02834.x.
4
[Retrospective analysis of Fusobacterium associated infections; experience at Aomori Prefectural Hospital with 108 cases from 1995 to 1999].[梭杆菌属相关感染的回顾性分析；青森县立医院1995年至1999年108例病例的经验]
Kansenshogaku Zasshi. 2002 Jan;76(1):23-31. doi: 10.11150/kansenshogakuzasshi1970.76.23.
5
Wound microbiology and associated approaches to wound management.伤口微生物学及相关的伤口处理方法。
Clin Microbiol Rev. 2001 Apr;14(2):244-69. doi: 10.1128/CMR.14.2.244-269.2001.
6
Fusobacterium bacteremia: clinical experience with 40 cases.
Clin Infect Dis. 1997 Sep;25 Suppl 2:S181-3. doi: 10.1086/516181.
7
Fusobacterial infections in children.儿童梭杆菌感染
J Infect. 1994 Mar;28(2):155-65. doi: 10.1016/s0163-4453(94)95600-6.
8
Gram-negative anaerobic bacilli: Their role in infection and patterns of susceptibility to antimicrobial agents. II. Little-known Fusobacterium species and miscellaneous genera.革兰氏阴性厌氧杆菌：它们在感染中的作用及对抗菌药物的敏感性模式。II. 鲜为人知的梭杆菌属菌种及其他属
Rev Infect Dis. 1981 May-Jun;3(3):599-626. doi: 10.1093/clinids/3.3.599.
9
Bacteremia due to Fusobacterium species.
Am J Med. 1983 Aug;75(2):225-31. doi: 10.1016/0002-9343(83)91196-8.
10
Anaerobic bacterial bacteremia: 12-year experience in two military hospitals.厌氧性细菌菌血症：两家军队医院的12年经验
J Infect Dis. 1989 Dec;160(6):1071-5. doi: 10.1093/infdis/160.6.1071.
Zotero 插件