Perlik Michał, Drews Krzysztof, Pieńskowski Wojciech
Klinika Perinatologii i Chorób Kobiecych, Ginekologiczno-Połozniczy Szpital Akademii Medycznej, ul. Polna 33, 60-535 Poznań, Poland.
Med Wieku Rozwoj. 2005 Jan-Mar;9(1):117-25.
Worldwide, Chlamydia trachomatis (CT) is the most common sexually transmitted bacteria. The improved understanding of CT pathophysiology in recent years became possible through DNA amplification technique and genome cloning. This paper updates informations on chlamydial infection in pregnant women, its pathophysiology, diagnostic methods, prevention and treatment. There is increasing evidence that Chlamydia trachomatis infection may result in a number of adverse pregnancy outcomes, including early and late abortion, infection of the foetus, stillbirth, premature rupture of membranes, prematurity and postpartum endometritis. Ectopic pregnancy is often associated with a previous tubal chlamydial infection. C. trachomatis infection in newborns may be acquired during pregnancy or during vaginal delivery, and it may result in neonatal conjunctivitis and/or pneumonia. We discuss benefits of early treatment of chlamydial infections in pregnant women and present guidelines for treatment. Screening should lead to early detection and treatment of men and women with chlamydial infection and thereby reduce the incidence of pelvic inflammatory disease, tubal infertility and ectopic pregnancy.
在全球范围内，沙眼衣原体（CT）是最常见的性传播细菌。近年来，通过DNA扩增技术和基因组克隆，人们对CT病理生理学有了更深入的了解。本文更新了有关孕妇衣原体感染及其病理生理学、诊断方法、预防和治疗的信息。越来越多的证据表明，沙眼衣原体感染可能导致多种不良妊娠结局，包括早期和晚期流产、胎儿感染、死产、胎膜早破、早产和产后子宫内膜炎。宫外孕常与既往输卵管衣原体感染有关。新生儿衣原体感染可能在孕期或阴道分娩期间获得，可能导致新生儿结膜炎和/或肺炎。我们讨论了孕妇衣原体感染早期治疗的益处，并给出了治疗指南。筛查应能早期发现并治疗衣原体感染的男性和女性，从而降低盆腔炎、输卵管性不孕和宫外孕的发病率。
