3T系统上自动单像素质子磁共振波谱算法的疗效评估。
Evaluation of efficacy of an automated single-voxel proton MRS algorithm on a 3T system.
作者信息
Ohkubo Masaki, Kimura Teruo, Matsuzawa Hitoshi, Matsuda Tsuyoshi, Kwee Ingrid L, Nakada Tsutomu
机构信息
Department of Radiological Technology, School of Health Sciences, Faculty of Medicine, University of Niigata, 2-746 Asahimachi-dohri, Niigata-shi, Niigata 951-8518, Japan.
出版信息
Magn Reson Med Sci. 2002 Jul 1;1(2):121-4. doi: 10.2463/mrms.1.121.
PURPOSE
To evaluate the efficacy of a fully automatic, single-voxel, proton MR spectroscopy algorithm on a 3.0T MR system.
METHODS
The PROBE/SVQ algorithm (GE Medical Systems) was evaluated on a General Electric (GE) Signa LX-3T system. Ten normal volunteers (female, 21.1+/-2.0 years old) participated in the study. Nine representative regions of interest were examined, namely, right and left frontal white matter; right and left parietal white matter; right and left basal ganglia; right and left dentate nucleus; and pons.
RESULTS
The mean coefficients of variation in all regions for the N-acetyl-aspartate to creatine ratio (NAA/Cr), choline to creatine ratio (Cho/Cr), and choline to N-acetyl-aspartate ratio (Cho/NAA) were 10.2+/-2.4%, 11.4+/-3.2% and 12.6+/-1.4%, respectively.
CONCLUSION
A fully automated spectroscopic examination under clinical setting utilizing the PROBE/SVQ algorithm appears to be a reliable method, extending the window of routine clinical assessment of brain metabolism.
目的
评估一种在3.0T磁共振（MR）系统上的全自动、单体素质子磁共振波谱算法的效能。
方法
在通用电气（GE）Signa LX - 3T系统上对PROBE/SVQ算法（GE医疗系统公司）进行评估。10名正常志愿者（女性，21.1±2.0岁）参与了该研究。检查了9个代表性感兴趣区域，即左右额叶白质；左右顶叶白质；左右基底神经节；左右齿状核；以及脑桥。
结果
所有区域中N - 乙酰天门冬氨酸与肌酸比值（NAA/Cr）、胆碱与肌酸比值（Cho/Cr）以及胆碱与N - 乙酰天门冬氨酸比值（Cho/NAA）的平均变异系数分别为10.2±2.4%、11.4±3.2%和12.6±1.4%。
结论
在临床环境下利用PROBE/SVQ算法进行的全自动波谱检查似乎是一种可靠的方法，拓宽了脑代谢常规临床评估的范围。
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