原发性眼内淋巴瘤的诊断与管理
Diagnosis and management of primary intraocular lymphoma.
作者信息
Levy-Clarke Grace A, Chan Chi-Chao, Nussenblatt Robert B
机构信息
Laboratory of Immunology, National Eye Institute, National Institutes of Health, 10 Center Drive, Building 10, Room 10N112, Bethesda, MD 20892, USA.
出版信息
Hematol Oncol Clin North Am. 2005 Aug;19(4):739-49, viii. doi: 10.1016/j.hoc.2005.05.011.
Primary intraocular lymphoma (PIOL) is a subset of primary central nervous system lymphoma. The incidence of PIOL has increased in the past 20 years. PIOL often presents as chronic uveitis that is resistant to corticosteroid therapy. Diagnosing PIOL can be challenging and requires an expert pathologist. The treatment of PIOL is difficult because of its high recurrence rate and refractory nature. The objective for the future is to improve diagnostic techniques and therapeutic success while minimizing ocular toxicities.
原发性眼内淋巴瘤（PIOL）是原发性中枢神经系统淋巴瘤的一个子集。在过去20年中，PIOL的发病率有所上升。PIOL常表现为对皮质类固醇治疗耐药的慢性葡萄膜炎。诊断PIOL具有挑战性，需要专业病理学家。由于PIOL的高复发率和难治性，其治疗困难。未来的目标是改进诊断技术，提高治疗成功率，同时将眼部毒性降至最低。
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