Schrag Stephanie, Schuchat Anne
Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Mailstop, C-23 Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Clin Perinatol. 2005 Sep;32(3):601-15. doi: 10.1016/j.clp.2005.05.005.
Neonatal sepsis is a leading infectious cause of infant mortality. While use of intrapartum antibiotic prophylaxis in the United States has led to dramatic declines in perinatal sepsis caused by the bacteria group B streptococcus, interventions to prevent perinatal sepsis due to other causes have not yet been clearly defined. This article synthesizes information on neonatal sepsis disease burden, trends, and risk factors and reviews current and potential approaches to neonatal sepsis prevention.
新生儿败血症是婴儿死亡的主要感染原因。在美国,虽然使用产时抗生素预防措施已使由B族链球菌引起的围产期败血症大幅下降,但预防其他原因导致的围产期败血症的干预措施尚未明确界定。本文综合了有关新生儿败血症疾病负担、趋势和风险因素的信息,并综述了预防新生儿败血症的现有方法和潜在方法。