Respiratory Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS C-23, Atlanta, GA 30333, USA.
Clin Perinatol. 2010 Jun;37(2):375-92. doi: 10.1016/j.clp.2010.02.002.
The burden of early-onset disease caused by group B Streptococcus (GBS) has decreased dramatically in the United States over the past 20 years. Universal culture-based screening at 35 to 37 weeks gestational age and use of intrapartum antibiotic prophylaxis are the cornerstones of prevention measures that have led to this decline. GBS, however, remains the leading cause of early-onset neonatal sepsis in the United States. Revised guidelines for prevention of perinatal GBS are planned for issuance in 2010. This article discusses implementation challenges for clinicians caring for pregnant women and newborns and presents an updated algorithm for neonatal management.
在美国，过去 20 年来，B 群链球菌（GBS）导致的早发性疾病负担已大幅降低。在妊娠 35 至 37 周时进行基于培养的普遍筛查，以及使用产时抗生素预防措施，是导致这种下降的预防措施的基石。然而，GBS 仍然是美国早发性新生儿败血症的主要原因。计划于 2010 年发布修订的围产期 GBS 预防指南。本文讨论了为照顾孕妇和新生儿的临床医生实施这些指南所面临的挑战，并提出了新生儿处理的更新算法。
