Károlyi A, Krompecher E
Országos Korányi és Pulmonológiai Intézet, Budapest.
Orv Hetil. 1992 May 31;133(22):1367-9.
The cost and effectiveness of examinations (sputum staining and culturing, antitest determination for Influenza A and B, RSV, Adenovirus, Chlamydia psittaci and pneumoniae, Coxiella burnetii, Mycoplasma pneumoniae and Legionella pneumophila, and determination for Streptococcus pneumoniae antigen) performed to explore the aetiology of community-acquired pneumonia in the case of 258 hospitalised patients were analysed. The aetiology could be determined in 44.2% of the cases. On the basis of prevailing prices in 1986-88 one pneumonia case with determinable aetiology costs 8111 Forint. The authors have come to the conclusion that in the present epidemiological situation in this country it is not worthwhile to look for so-called non-bacterial microorganisms routinely, because of their rarely occurrence (16.7%) the cost per one positive finding is unrealistically high. Comparing the cost and the practical use the examinations applied the rational choice seems to be to culture the sputum with deep airway origin and to determine the Streptococcus pneumoniae antigen routinely. In the case of suspicion of non-bacterial origin to perform complement fixation test for Mycoplasma pneumoniae and in a severe clinical state to culture the blood is recommended.
对258例住院患者进行的旨在探究社区获得性肺炎病因的检查(痰涂片和培养、甲型和乙型流感病毒、呼吸道合胞病毒、腺病毒、鹦鹉热衣原体和肺炎衣原体、伯氏考克斯体、肺炎支原体和嗜肺军团菌抗体检测以及肺炎链球菌抗原检测)的成本和效果进行了分析。44.2%的病例能够确定病因。根据1986 - 1988年的现行价格,一例病因可确定的肺炎病例花费8111福林。作者得出结论,在该国目前的流行病学情况下,常规寻找所谓的非细菌性微生物是不值得的,因为它们很少出现(16.7%),每一项阳性结果的成本高得离谱。比较所应用检查的成本和实际用途,合理的选择似乎是对深部气道来源的痰液进行培养并常规检测肺炎链球菌抗原。怀疑非细菌来源时,建议进行肺炎支原体补体结合试验,在临床症状严重时建议进行血培养。