Al-Ali Musa K, Batchoun Raymond G, Al-Nour Tarig M
Department of Medicine, Faculty of Medicine, Jordan University of Science and Technology, PO Box 3030, Irbid 22110, Jordan.
Saudi Med J. 2006 Jun;27(6):813-6.
To ascertain the causative organisms of community acquired pneumonia (CAP) in Jordanian patients requiring hospital admission.
A prospective study of both adults and children admitted to Princess Basma and Princess Rahma Teaching Hospitals in Irbid, Jordan with a diagnosis of CAP over a 6-month period from April to October 2002.
A total of 35 adult patients were admitted with a mean age of 47 years, and 63 children with a mean age of 3 years. A pathogen was isolated from 25 (71%) adults, and from 17 (27%) children, and sputum cultures gave the best diagnostic yield. In adults Streptococcus pneumoniae was the most common isolate (26%), followed by Chlamydia pneumoniae (23%), Haemophilus influenzae (17%), Mycoplasma pneumoniae (9%), and Legionella pneumophila and Klebsiella pneumoniae (6%) each. Seven of the 9 gram negative isolates were from patients with some co morbid illness. While in children, Chlamydia pneumoniae was the most common (14%), followed by Mycoplasma pneumoniae (6%), and Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa (3%) each.
Streptococcus pneumoniae and atypical microorganisms are the most common cause of CAP in previously healthy adults; while in those with associated co morbid illness, gram negative organisms are the likely cause. In children, the overall detection rate of causative organisms was low with atypical microorganisms being the most common.
确定约旦需住院治疗的社区获得性肺炎（CAP）患者的致病微生物。
对2002年4月至10月期间在约旦伊尔比德的巴斯玛公主和拉赫玛公主教学医院收治的诊断为CAP的成人和儿童进行前瞻性研究。
共收治35例成年患者，平均年龄47岁，63例儿童患者，平均年龄3岁。从25例（71%）成人患者和17例（27%）儿童患者中分离出病原体，痰培养的诊断阳性率最高。在成人中，肺炎链球菌是最常见的分离菌（26%），其次是肺炎衣原体（23%）、流感嗜血杆菌（17%）、肺炎支原体（9%）以及嗜肺军团菌和肺炎克雷伯菌（各6%）。9株革兰阴性菌分离株中有7株来自患有某些合并症的患者。而在儿童中，肺炎衣原体是最常见的（14%），其次是肺炎支原体（6%），肺炎链球菌、流感嗜血杆菌和铜绿假单胞菌（各3%）。
肺炎链球菌和非典型微生物是既往健康成人CAP的最常见病因；而在患有合并症的患者中，革兰阴性菌可能是病因。在儿童中，致病微生物的总体检出率较低，非典型微生物最为常见。
