[癌基因和抗癌基因在皮肤病学中的作用]
[Role of oncogenes and anti-oncogenes in dermatology].
作者信息
Basset-Séguin N, Guillot B, Dereure O, Moles J P, Guilhou J J
机构信息
Laboratoire de Dermatologie Moléculaire, CNRS/CRBM, Montpellier, France.
出版信息
Pathol Biol (Paris). 1992 Feb;40(2):184-91.
PMID:1608659
Abstract
Cell growth is controlled by two types of genes, i.e., activating genes (oncogenes) and negative regulator genes (antioncogenes). Studies have shown that malignant transformation of a cell can result from either increased oncogene activity or decreased antioncogene activity. Current knowledge of genes relevant to dermatology is discussed.
摘要
细胞生长受两类基因控制，即激活基因（癌基因）和负调控基因（抑癌基因）。研究表明，细胞的恶性转化可能源于癌基因活性增加或抑癌基因活性降低。本文讨论了目前与皮肤病学相关的基因知识。
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