AuBuchon James P
Department of Pathology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, New Hampshire 03756, USA.
Transfusion. 2005 Aug;45(2 Suppl):28S-32S. doi: 10.1111/j.1537-2995.2005.00528.x.
The transfusion of radiolabeled red cells and platelets (PLTs) allows for the accurate determination of in vivo recovery and survival after subjecting the cells to an experimental collection, processing, or storage system. The techniques utilized in these protocols have undergone refinement over the past several decades, and these improvements have reduced interlaboratory variability and improved the accuracy of the techniques. At present, the field is evolving toward new applications of these radiolabeling techniques, including, for PLTs, the use of freshly collected autologous PLTs as the standard-setting PLTs against which the "test" PLTs can be compared. The contribution of the National Blood Foundation in supporting research in these fields is acknowledged with appreciation because its efforts have helped advance not only the science involved but also the scientists engaged in this research.
输注放射性标记的红细胞和血小板可准确测定细胞经过实验性采集、处理或储存系统后的体内回收率和存活率。在过去几十年里，这些方案中使用的技术不断完善，这些改进减少了实验室间的差异，提高了技术的准确性。目前，该领域正在朝着这些放射性标记技术的新应用发展，对于血小板而言，包括使用新鲜采集的自体血小板作为标准对照血小板，以便与“测试”血小板进行比较。国家血液基金会在支持这些领域研究方面所做的贡献得到了诚挚认可，因为其努力不仅推动了相关科学的发展，也助力了从事这项研究的科学家。
