Dillon Shane C, Zhang Xing, Trievel Raymond C, Cheng Xiaodong
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Genome Biol. 2005;6(8):227. doi: 10.1186/gb-2005-6-8-227. Epub 2005 Aug 2.
The SET-domain protein methyltransferase superfamily includes all but one of the proteins known to methylate histones on lysine. Histone methylation is important in the regulation of chromatin and gene expression.
SET结构域蛋白甲基转移酶超家族包含了除一种蛋白外的所有已知可使组蛋白赖氨酸发生甲基化的蛋白。组蛋白甲基化在染色质调控和基因表达中起着重要作用。