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果蝇中光噪声诱导的阈上昼夜节律振荡和相干共振。

Light-noise-induced suprathreshold circadian oscillations and coherent resonance in Drosophila.

作者信息

Yi Ming, Jia Ya

机构信息

Department of Physics, Central China Normal University, Wuhan.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jul;72(1 Pt 1):012902. doi: 10.1103/PhysRevE.72.012902. Epub 2005 Jul 18.

DOI:10.1103/PhysRevE.72.012902
PMID:16090019
Abstract

Based on a reduced circadian oscillator model in Drosophila [Smolen, Biophys. J. 83, 2349 (2002)], the effects of light noise and time delay on a circadian oscillator near a Hopf bifurcation are studied by using numerical computation. When the light-controlled parameter is suprathreshold, it was found that the circadian oscillations can be induced by light fluctuation. There is an optimal light noise intensity at which a remarkable coherent circadian oscillation is observed, which implies a significant resonance phenomenon in the sense of preferred biological circadian oscillations. Time delay can control the coherence of noise-induced circadian oscillations and the strength of coherent resonance achieves a maximum under a moderate time delay.

摘要

基于果蝇中简化的昼夜节律振荡器模型[斯莫伦,《生物物理杂志》83卷,2349页(2002年)],通过数值计算研究了光噪声和时间延迟对霍普夫分岔附近昼夜节律振荡器的影响。当光控参数高于阈值时,发现光波动可诱导昼夜节律振荡。存在一个最佳光噪声强度,在该强度下可观察到显著的相干昼夜节律振荡,这意味着在优选的生物昼夜节律振荡意义上存在显著的共振现象。时间延迟可控制噪声诱导的昼夜节律振荡的相干性,并且在适度的时间延迟下相干共振强度达到最大值。

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