Dodd G D, Ledesma-Medina J, Baron R L, Fuhrman C R
Department of Radiology, University of Pittsburgh Medical Center, Presbyterian University Hospital, PA 15213.
Radiology. 1992 Jul;184(1):65-9. doi: 10.1148/radiology.184.1.1609104.
Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation and immunosuppression. Early diagnosis and treatment greatly affect prognosis. Chest radiographs (n = 13), chest computed tomographic (CT) scans (n = 2), or both (n = 20) from 35 patients with intrathoracic PTLD were retrospectively studied to define the intrathoracic manifestations of this disorder. Intrathoracic abnormalities consisted of pulmonary nodules (16 patients), patchy air-space consolidation (three patients), mediastinal and hilar adenopathy (17 patients), thymic enlargement (two patients), pericardial thickening and/or effusions (two patients), and pleural effusions (four patients). Multiple, well-circumscribed pulmonary nodules with or without mediastinal adenopathy are highly suggestive of PTLD. However, pathologic examination is usually necessary for a definitive diagnosis.
移植后淋巴组织增生性疾病（PTLD）是器官移植和免疫抑制的一种严重并发症。早期诊断和治疗对预后有很大影响。对35例胸内PTLD患者的胸部X线片（n = 13）、胸部计算机断层扫描（CT）（n = 2）或两者（n = 20）进行回顾性研究，以确定该疾病的胸内表现。胸内异常包括肺结节（16例）、斑片状气腔实变（3例）、纵隔和肺门淋巴结肿大（17例）、胸腺肿大（2例）、心包增厚和/或积液（2例）以及胸腔积液（4例）。有或无纵隔淋巴结肿大的多发、边界清晰的肺结节高度提示PTLD。然而，明确诊断通常需要病理检查。
